ID   A0A1I8H9A7_9PLAT        Unreviewed;       951 AA.
AC   A0A1I8H9A7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=RING-type domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0004906-snap-gene-0.13-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0004906-snap-gene-0.13-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0004906-snap-gene-0.13-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the TRIM/RBCC family.
CC       {ECO:0000256|ARBA:ARBA00008518}.
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DR   AlphaFoldDB; A0A1I8H9A7; -.
DR   WBParaSite; maker-uti_cns_0004906-snap-gene-0.13-mRNA-1; maker-uti_cns_0004906-snap-gene-0.13-mRNA-1; maker-uti_cns_0004906-snap-gene-0.13.
DR   Proteomes; UP000095280; Unplaced.
DR   CDD; cd05819; NHL; 1.
DR   CDD; cd16449; RING-HC; 1.
DR   Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR001258; NHL_repeat.
DR   InterPro; IPR011044; Quino_amine_DH_bsu.
DR   InterPro; IPR047153; TRIM45/56/19.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR25462:SF302; B BOX-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   PROSITE; PS51125; NHL; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          399..482
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REPEAT          771..813
FT                   /note="NHL"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT   REGION          354..382
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          559..593
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        354..374
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   951 AA;  106544 MW;  A50190D81212EBF2 CRC64;
     QQQPQVNYIS SSSSRRRSRS YRVLLSQSRP RVDEAEKCQA AVDLMVGRRS NGNGPPGRLP
     SRSGRRFCLN NYGRLKRIAE CNTRRRLFEE VEQQRRLKAE GGGCPSAFEA RRRAVRRRLK
     ASREARAAAA AEAARLASTG DDGRAEAVME KLLYEDCSGR VLSHQVLRRR RNRGGRFFLV
     LLIDSRLSQT LSRFWRPDPT QALGQFVVQL IKEVSSAGLG FCKIVGSVRG FGQALQFRQA
     GVELGTAGQH RGHNTQLTQQ LSIGLAPSLE RIRNHLTDEL QVGVGDIRHA AAAIDAQAGT
     LTFCTSRLQR RTANSSCWSH GCRDSSGCQL PPRRGRFSGG CGWQAAVVET PAEFRRQKQQ
     QQQQQKQKQI QPSVWRKRAS DAASPATDAL KELVGDCTCP ICQEVYTNPH QLACGHTFCL
     KCFDKLKRKW EKRTTNGGGG GGGGGSGSDG EMLSLGQMLL QFSSSVAGRS GDSDPLQCPV
     CRTSVDPHRP LKPDQTVRSL LHTLKTVKAG CCQESDCWNK RQVCCTQCAC GLCAEHHKAK
     MESIRSGCDE LAQEAEKFLL AKSEEFEKMQ SQLTDAETKL EELQQAMLKS QQERFSMCSD
     QLAAVRQRTE QEQNERTNIG AELNEEAKKL RQLLENETGH IGPEVGFDND KMTTEQDTVL
     QAVSVRILKR PYAERSEKFK PMVIKKTKRG EPWEVRLLQD DKLLVNYKGF PTRRLHIFNA
     GTLKETDMIE LQLNQGQFPG QICVCRQREK ILASDPKNHC VYEFNYGGRM TGQFGSKGSE
     PGQLHTPKGM YIYENILYVV DSKNKRIQLF DMEQDYKNVG SVEHDSISTS IQAVFVGPAS
     IVICDRGSDS LIVFDRVSKR YLKKLPAGGE PFDACTDRFD NMIVSLTRER KIRIYDSTVT
     HCINTFDIGS AIDSDSEKLQ NYLHGVAFDP NSDRLFVAEA FAKRLLRFDM T
//