ID A0A1I8HEE3_9PLAT Unreviewed; 5274 AA.
AC A0A1I8HEE3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=DDE_Tnp_1_7 domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0005812-snap-gene-0.10-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0005812-snap-gene-0.10-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0005812-snap-gene-0.10-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR WBParaSite; maker-uti_cns_0005812-snap-gene-0.10-mRNA-1; maker-uti_cns_0005812-snap-gene-0.10-mRNA-1; maker-uti_cns_0005812-snap-gene-0.10.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029526; PGBD.
DR PANTHER; PTHR46599:SF3; LD40589P; 1.
DR PANTHER; PTHR46599; PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4; 1.
DR Pfam; PF13843; DDE_Tnp_1_7; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1373..1391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1525..1543
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2416..2777
FT /note="PiggyBac transposable element-derived protein"
FT /evidence="ECO:0000259|Pfam:PF13843"
FT REGION 93..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..965
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1013..1040
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1157..1205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2289..2308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2897..2920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3204..3237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3357..3383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4595..4625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4927..4964
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5043..5080
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5124..5274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..776
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1186..1205
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3364..3383
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4603..4619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5062..5076
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5156..5180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5209..5234
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5274 AA; 572594 MW; D7FF17E606272C32 CRC64;
LLEPVKVGFV RLLELAQLLD LNKLFLVDDE LAFVCVQVAL RLALHLQRVE TKSRPIDFCL
GDPSSFLNSS NACVLEGGVP GLAAAAAAGS ELPTASRVPS ESAPAAAPEE EPPPAPSGCW
RCFLEEAAVA AAASRRLLCR KTPDSSMPTS LRAAMPKLRP SRSPTASPPT PDVDGPSERA
APSGGVAATP PACWAASSSC RRASASSRLA KQASRNSSKT AWICRMLVAI DVPLNLLPQL
EPLLLGDGFV VDDFNALNKQ SLKIGEYDKK LLSYLKSLKA KTAAHTGIGA LVLHRLAGNA
AHSLGESHCG NLQSNAAPMA AHQRVSSLIL HQWRLIKECP GTHSFVKLPD VAPDVGDEDG
LAAAADAVLQ VVRQLALPVR HVVAVLLRQR DDRLLEKRQR LVDVGGLLLS FPRAQGFLQP
LGSGQIYEVN LGHCVLGIGL EPGPGLQIQM RSPPNHLKQQ VQRLLLRLRQ VDIQAFDVDA
AVLLGDDQRA AGLLAVGHGG QQVQHGVVVD LQVMRTVMAR SDLASISLYR WLSALGTRPR
LWNISVAPVM LTRSGLAVAH DGAVVARQAA FDEVGPHSLV DLLLRGVGED AVGAEGPVGA
LVVGEAALLR LLVAAGPRHA DLQRPALRVQ LDGVVGEVLA GPDSNPDLHL LAAVAATFHL
LALQRTGHRR TDDLRQSSSG MHQIQCRQLN WTCNGDGGAG GHADSLGGVA GQDGGGHGRA
ARGDPGNASG GGHAGDPDGV AAGLADPVAE QGAKEPRLGL QQRPAGQQQR HGQHSSGGKA
GCTRCWIALD RTCQPGCSSS QLCRTNGITS MLMTVTSMSV TSGDFMLAKD CQWKPVEASD
KPTLKREPCR TDRSTEYRLN SIGTALQCDT EALGVEAAYL IRSDSLYLTA LDSDDFRQEF
AVDPGGGRLA GRLLKPNCTV PAAPGRIETC RVPGSRPVLI GWPRKARTRR KNSPGTSSSS
CGRAGSLSRW QVSRWNSTAW QSVPQRTMQS VRHLLTGCTG PMVDLPTRPV MSRVGLSTKQ
PNGLNSTPRE QRKATQQQKS GRINEACMSS VYGAKGLRVY CCYTGCFMHF ARSHWGGGVD
AAVMTRKFRD DQKGGKMRYT WSQQVYIVTR CLGQNVYRLG GLTSVTLRPS ESSDQIRQSL
SKLRLIATTS DKDAESLRYK TEAVGREQNY GPGVTNQNAS KREPKGNRPP AGKLDKTKNR
EKKARPNTLS YIARVTTPQN PLKPGGGRLA GRLLKPNCTV PAAPGRIETC RVPGSRPVLI
GWLRKARFVT KVALLALLLI GGPQLQAEAG IIGAVASYGV CQTGCNTVWV ACVAAAGGVA
GVSTGGTAVP AAILACNAAN GVCMAGCASY VKLTTVTSVS GLLYNVSLSS PSLLLLLLLL
VFRLFLAFVN IGRHFSRRPR RVAAQGQLLL WLLLQRLLSK AGSAACLNEC TVSQALLAWC
SSSPIPRAAV ESIIRSEMSR GTRATSVLVP LSACAVFCDS LPTRDEASEG AMYAAACCEP
TGSHSSWPPS PFIGRKTSSV SSRSSYVITF LAVICCSASL MKIRTVTTSR ALCRAFCCGH
FHPNCEVFLS LHGSQQPWGV VIAAEGICVA NAASSGHEAA ESLALRDHIA VKEADGHGVC
LLFVLLLIQS ISGHRGEILC VSETRTLFCG ALRLTDERKN FLSIMMSGWI CSAFELAVSI
ASLLDAGLSL ELDVAVRVNL GVLSLIRFAR VGKISKQSLG SDFKVCELPD AQHPPDLLIA
LVQLLLPRRR RVQQDIVGFV DPMVLRPNLR DENRSPLGER QAGNPDPDAR LVGRELLQAS
LPVDGVQHVA VDDAEILQQH AVTFLYHTLD LLPVGAFHHL VNVANVAALV VIEHHHELEA
VKVVDAAGWL QQEAGALEQA IVVVVVPIQL AHNHADALGG VSVEDLAVTD PAVPVGVPRH
DDLLLREGDV AAVEHSGKGV AQLYPVTVFL LRLISQLSPL ATGLVTYSTA MRLGRPRLYF
NRHTWKRLAL RPAHGLPAES FLSQRSPLQP AWQLQRNEAA ELMQRPWSPH GLMVEDRDRA
SGSLLNGCVT GLDMPPIFEP KLTLSEFLIH GRAILATEQL RANSPKRRVS PFEVAGGANA
QIDLRIAGRD ALLQEEQAVA VVAAGQPGVG HRVLHELHVP WCGSSARPGD GAESNSRSEN
SETNCSIASW GRWLNSDLSI IRANSAKQAT LPLMQLSLRR GSKPIFTQLK VASVSVIVEA
VCCSRVVSVI VEQELVVGAV EPSAHGVAGG AGEGAKGLQP RQVVFAAHIR DEAAGLNVGS
GVEQPAALAG AAAETEREEL RSAAGSKSGG QTGLSACVKM CKNDFERFLA EHFDTDTDPE
FEEGDDSFFT DDEDETEQGG MEMQEVDEGL AAAHGATNVW HACHPGQDQK PNQDPEFLGM
PGVNPDLPQP ENADEDPVAF SRMFLTPELL QKLCDWTNAR AWREFEDLQD EQLPSRFSSW
KDVTVNEMSK FVAMSLYMGV VKKPEVTHYW SKSEFYSTPF FQQQACLPRD RFQQISSLLR
FYDCSNFDAA DPLAKARPFI NCVSRICRNV YMPEKELSVD EELLKKARYG IKIYCLCEAK
TGYVCNFLVH SSRAENDKFG QDLGCEGLSM SEKVLVETCR YVLDLGYHVV CDSWFGSHRL
ADYLLHHGTL LTCTVRANRG VPVELRDLAV PAPGCAFMRS GSVLAVKYVV RKASGTKTVY
FIDTKNAAAI QHVHRTIQGN HEVVELKPLT ATSYNSFMGG VDKLDSGLQP YSPNRRTQKW
FAKLGAHFFL VLVRNGWVVY QSRGGSYDFL KFLELTIKGF IQTTGPARSR QIQAQPGTGP
NRQQHLLKRL RPTDKFIAPL SVDRCRIDVG ASYLGRERLY RAHVYMECSP PGWNRLCSPD
RFVQACEPMW PARLSPIPST RSADMSPADS KGAAAGPEAP VQRELAPVAG TAAFLSRVRG
HAGGPPAAAQ HAGRLSAYIR HRPSSKADQL RRLSNAHLRA FELGLSVAWN FQLHQPEDAC
RRLPLKLSSS HTVSLASSFI TPDCSSSNLP STSCLTWLMA GRIRSICCCS SGTKACAWPC
DRYRPCTACT RSRSCWCASS GEQVSMLIAR ATCCTFGGQF GSRLGEVWPR LLLLLLLLLL
ELRQLLLLSR HCWATTLIWS RPFSFRSGVS RMCTPSCSMR SFTKMAERGF SGSCGSRRAR
RERRPKPIGF RCFGGRAAAA ASAASAAPKS EAGPPASSSL TGAPAPLPTA APPRPVTSSM
MRVRDTLAAV LSSASAAAEY SVARILISAV MGLDCMYVYR VGRRSVGAVM QLNWFVEFKP
KICLRLGARL RLGRRLPGLD RQVFRRGQAT SVFQIGRNCL ESLAPVQLLL ALPTEHPQAG
DRVQPDDTNK NSTMVGSQQM RSVSTSRNKR RAIKWSMSIA LRFAFRRVFL RNSSEKLQVA
SQVLPTMMAT LCRVQPCCLK RCTRSYDRKA KMVTETSLLM VARMAQTVHR LEARHWSSSA
RLRFKIRKSV VFFSSFFTTR HAMTNRLPNK ARQPKIQTMT CCARSPSRSS HELKPSAGGV
QFTAMPSARQ QNLKESWVPA QIQVARAVAI EEKIVRQAGY AHIREVEVHY EWQVSEAEAL
NGYYRVTSNQ QRVQMYQTGP DMAWYDADFV VTQIKVAQID QVKEQANSNL FKADTAHLKQ
AKQGQVVKVT RLRRDLRVPT QVQRPGQRRD SLIDVEVQWT QALRDVATTV AGLPAFHVAE
GLVLAVSTVS DPVAGILRRH ADVERAKYAF AKQQMLSTHQ RRLRAVDLIG PIAAVLHAVA
QPVDRDAVAR GALEETPTAK ARTVAHTAAQ VLHVRADLLA KLPPIEDARV APGKTLHRSH
WLSGQSGNFC EPGSMTSSPR VQLLARRHVM ASSSSRLPGQ STCVSFTRPF GMHRPLRHWK
PLQVSQFCSS YLPLLIGNAL LGSLALEFVR FARAELAVGL VQACAAVDLV VAQPRPADPL
QMSAAAVALE ESIDNFRAAV HFVLATFERN EFVPSRQANW LLRQPTCSAT GLRSQSTDRV
GSLPISPPVR FHGTTVESQQ HVALALVLDP VVCAGGSLRP DLLQLLVEMA LQFYLVIFVS
RPFADVALAF DLDVAGHLDP VGVVPRVVQH HAHARVEIVH VEALVLLRNS NCRSELRSHL
RPSPQPDVDE HVRVGERLRV PFVEQHLFDG VHLILALDAD QRVVSLLNEP LMDSDMRSLL
FRHTSRVEEQ LALSNIDKGP GRLWVSLSNM SAVKNRFVNN ENTRYGSGVT KHDAVGVNNF
LFLVPEVHVV AFVPVYIKAE DDTVRDHLFL PSRRLTRSAL GLSIETMLSV VASRFCSPLM
QCTGRYCDKV TLKPALPNGV LSAVAQGADA AAAFDAGVES GLFKDQTIPN ARLVVRLFNV
QVAELDLEQG AGLSGADEHG AVDIRWIEIA IVAYRRAVGI GRLLGWRSSL VLSTASAGQL
PGLLGESLQF LLERETAAGR RGKGDAEVGR QLARSSWRPP RAYRSHQRCE SNVQSDEFND
SVAQLIALQC GYGFRVRLPS FLVARPRSCQ NKHQCSTCTV LACSRLSLSR CALSVSRWLW
RAAWSSSATV FVLPTAARSC IRLKSAAEVG RDPPGYFNVR HHRPSRPSSS LSAKPEGRDS
TPGTPSLAPP AFKAAWSAWL CRCLWSGFES PCISTPCIRS SWGKRCPKPP PHLIHRAVLH
RPLLHRGRGV VRVRGAGLGV AVHQHAMQEL LLVQLAGLLT CGRVRALQLL ASLLSVLDSV
AVAGLGVAVH QHTVHAVHAD AGAWGEGQRM GRATDGAGLR VRQGSVGSVT WQRVLVSSLD
PACPSGAALN HRSVCEDTAG TQQEYSRNTA GIQQDYSRIT AGIQQEYSRN TAGIQQEYSR
NTAGIAGIQQ EYSRNTAGIQ QEYSRNTARL QQEYSRNTAG IQQDYSRNTA GIQQDYSRNT
AGIQQEYSRN EAGKSAAGKT GRAHGSKGAA AKDTPGGAKA ESSRADQLID RCGWLGLSAA
PQRIISGTNP RMSCPSPLKK LGAAGASVGS GLSVARQFNR VSRLEAEHEE WLRRTLQRVA
LAASGSTDGS REERLDSEKA SQPSGAAVSS HQLRQQQRDR LIQERRERGR SLLSWQQQQQ
QEAAAADTAE AGTSLTVKSL IGSRSDAANA RDRGSEKATS LSKQLKAPPP LLTLSPTPFI
QQAAPAVKSE RQQLQPVAKP HQTQLHRPRL RGPAVRSRQL EHSSPEQRRQ EPQLLSIGQA
PGIQQDQRAA QAQAAEQSME LADYVRTRQP AMRLREPTLV QPRNPVNSPE LLAP
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