ID A0A1I8HEG8_9PLAT Unreviewed; 551 AA.
AC A0A1I8HEG8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Fork-head domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0005624-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0005624-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0005624-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR AlphaFoldDB; A0A1I8HEG8; -.
DR WBParaSite; maker-uti_cns_0005624-snap-gene-0.2-mRNA-1; maker-uti_cns_0005624-snap-gene-0.2-mRNA-1; maker-uti_cns_0005624-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF401; FORKHEAD BOX C1-A-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT DOMAIN 306..400
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 306..400
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 68..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 486..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..551
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 58438 MW; E5040105D26D8367 CRC64;
PLKVDLVCLE SRVCLCSKGS GQELPPPAAL RLMAAPSTAG LDTSVAASPG AENINPPPHL
KLKRNLLPAG SAERPGPHWG RRTGPGSCLG KIRRQLMKAA SQGASPLVRS MAGLKNRSGE
LSLAGGLQQP LRSMQVASTL EYPQQQQQQQ QAISRQSPQS HHSATSPFDE GPVNAIAASS
SGSSAPAGAT AAAAAAYLQA QQGHPYTAHS MGLWQQQQQQ DHQTTPREGS EEATDASAAA
AAAAAAAAAA AAVMPAFAHG YYASHHAAPA GGVYAQHHLQ HHHHHQQCYS ASRYSPYGPG
GKDLVKPPYS YIALITMSIT AQPDKKITLN GIYQFIMDRF PYYRENKQGW QNSIRHNLSL
NECFVKVARD DKKPGKGSYW TLDPEAYNMF DNGSYLRRRR RFKKKDSAMR EEKGRSQAAA
VVAAAAAAAA AAAAGNADLA QTETSAAGDG AGEAKENQPG GGCRIYELAE GGSPQPEALL
EATAVSDGGH SAGESSSERN LDLSRLKSDD PLIEQQLLHR SAVAAEPLRT EQDRLLNQAL
APNTRRALRS Q
//
