ID A0A1I8HEV0_9PLAT Unreviewed; 450 AA.
AC A0A1I8HEV0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=T-box domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0005765-snap-gene-0.5-mRNA-1};
GN ORFNames=BOX15_Mlig018453g1 {ECO:0000313|EMBL:PAA70406.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0005765-snap-gene-0.5-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0005765-snap-gene-0.5-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:PAA70406.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA70406.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA70406.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR EMBL; NIVC01001239; PAA70406.1; -; Genomic_DNA.
DR STRING; 282301.A0A1I8HEV0; -.
DR WBParaSite; maker-uti_cns_0005765-snap-gene-0.5-mRNA-1; maker-uti_cns_0005765-snap-gene-0.5-mRNA-1; maker-uti_cns_0005765-snap-gene-0.5.
DR Proteomes; UP000095280; Unplaced.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00182; T-box; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR PANTHER; PTHR11267:SF129; LP04777P-RELATED; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 41..228
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 409..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 50545 MW; 0943D24545EBED4F CRC64;
MQHQSPTSSA DYAALIQQAP QLQPYYLTTL APSGEQVHVA LSNSSTWRKF SRQNTEMIVT
KVGRRMFPTL SLDIQGLDPA KKYEVYVTLM LADRHTLKYQ RGVWLPNGQG EVYPPPGCTV
GLAYVHPDSP APGKHWTRQE VAFMRLKLTN KLDCFANEPA RNGTMIFAYS MHKYLPVVHI
RELSRNATAF YTAVTFPGTE FITVTAYQNP ELTDLKIQFN PYAKGIRNQG DRSGPLLIDS
FRPTVQALQQ QLQLPSCQPR QDVREPDIVE FGSYPEQTDS AYGYWSQQQQ QSHRSRRLYR
PYSAVEASPT VLAASSTIPS SEVDSSSSAA CAYTPSPYQA SYQPHYQPHH QQFYYQPAYN
YHLVDVAQMG DAQYEASGHS NEQQLSPYFH HHLQGAGATV PLPLLSTPLQ QQQQPPQQQQ
HVQPPQQQSC PTDSSSLSTV SFSSPPTCDL
//
