ID   A0A1I8HGV9_9PLAT        Unreviewed;       582 AA.
AC   A0A1I8HGV9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=HGTP_anticodon domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0006101-snap-gene-0.4-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0006101-snap-gene-0.4-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0006101-snap-gene-0.4-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00008226}.
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DR   AlphaFoldDB; A0A1I8HGV9; -.
DR   WBParaSite; maker-uti_cns_0006101-snap-gene-0.4-mRNA-1; maker-uti_cns_0006101-snap-gene-0.4-mRNA-1; maker-uti_cns_0006101-snap-gene-0.4.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00774; GlyRS-like_core; 1.
DR   CDD; cd00858; GlyRS_anticodon; 1.
DR   Gene3D; 3.30.40.230; -; 1.
DR   Gene3D; 3.30.720.200; -; 1.
DR   Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004154; Anticodon-bd.
DR   InterPro; IPR036621; Anticodon-bd_dom_sf.
DR   InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR   InterPro; IPR033731; GlyRS-like_core.
DR   InterPro; IPR002315; tRNA-synt_gly.
DR   NCBIfam; TIGR00389; glyS_dimeric; 1.
DR   PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR   Pfam; PF03129; HGTP_anticodon; 1.
DR   PRINTS; PR01043; TRNASYNTHGLY.
DR   SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT   DOMAIN          460..552
FT                   /note="Anticodon-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03129"
SQ   SEQUENCE   582 AA;  65519 MW;  AE5C759E93FAA9FF CRC64;
     ILSRKLQYIV EEVMEGFDRN KLETLLKQRF FYDQSFAIYG GVQGLYDFGP MGCAVKANLL
     QEWRNFFVLE EQMLEMDCSM LTPGAGAEGL RPRGEVKDLK TGECFRADHV VKQFLEKLEA
     DPKTPQDRRD EARRILNSLD NLDGAGLQEV IVKFGIKSPQ SGNEISEPQQ FNLMFQVSIG
     PAGNIKGYLR PETAQGIFVN FKRLLEFNQG RLPVREFTMA EIEHFLDPAD KSHPKFASAV
     SAGVIANQTL AYFMARIFLF MVRCGVDRQR LRFRQHLSNE MAHYACDCWD AECLTSYGWI
     ECVGCADRSA YDLTQHSKAC GAQLVAEKML AEPQVVVANE AVINKGVVGR TFKADAVHVT
     QYLSSLEEAD LNSLATELES LGSASREIGG SERKLTPDMV SVRRTERTVH RLEFVPSVIE
     PSFGIGRIMY VIFEHSFRAR EGDEARTYLS LPPVIAPYKC SVLQLSNNPK LREMATAMSQ
     ALTQAGLSHR IDDSSVSIGK RYARTDQIAI PYGVTIDFDS INKTPATATL RERDSMRQVR
     VEVEKIPGIV QQLVQERLTW AQVMEAYPVF EQQETIKDTD GN
//