ID   A0A1I8HHA8_9PLAT        Unreviewed;      1108 AA.
AC   A0A1I8HHA8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Nucleoprotein TPR {ECO:0000256|ARBA:ARBA00019789};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0006064-snap-gene-0.3-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0006064-snap-gene-0.3-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the TPR family. {ECO:0000256|ARBA:ARBA00005274}.
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DR   AlphaFoldDB; A0A1I8HHA8; -.
DR   WBParaSite; maker-uti_cns_0006064-snap-gene-0.3-mRNA-1; maker-uti_cns_0006064-snap-gene-0.3-mRNA-1; maker-uti_cns_0006064-snap-gene-0.3.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0034399; C:nuclear periphery; IEA:UniProt.
DR   GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   InterPro; IPR012929; TPR/MLP1.
DR   PANTHER; PTHR18898:SF2; NUCLEOPROTEIN TPR; 1.
DR   PANTHER; PTHR18898; NUCLEOPROTEIN TPR-RELATED; 1.
DR   Pfam; PF07926; TPR_MLP1_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   DOMAIN          989..1103
FT                   /note="Nucleoprotein TPR/MLP1"
FT                   /evidence="ECO:0000259|Pfam:PF07926"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          436..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          574..603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          851..890
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          96..199
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          232..298
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          508..545
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          641..752
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          778..844
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          983..1105
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        585..603
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        851..871
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        872..890
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1108 AA;  121543 MW;  C0F67E6B591AD54E CRC64;
     SASAPDEEAG PTSSSMEPTE ASEAGISRAS SEAISMINAD VWASLSPEQQ AGVRAAVDHL
     SGELARERER RRVVCIDSEQ QVFDAESRTS GLSARLASLQ AEAEAATARA AELQQQLAGA
     ETVRREADEA RSACSAAVQR AESLTAELAD VQRRLDDAEA AKDAAVGKLE ELERERLTLA
     LQLDENESDR EERQQLEESY QRQLLAERAA AELCKTSAEE QSARCAELSS AAEGMRARLS
     EFGRERESIE RRFSAQLSEA AGRQSELEAT VNQLRAQLDE ARSEVDRLRA GIGALSEAEI
     ERLAPAAAAT SRMLKRGKTL TQIYAEHVEV QGQLSAARLE ADKANLAVAH ILEEVQAKVP
     VIRRRQEECR RVRLSAVQLA KRLDESVAQM CDLKRTNEEL ERKAAFFERE NARLKARAGD
     LGEQVASLLA KIESSGGRPL AESGSSEAEA AQPEAGKEPA DSQQQAALDL SALSEQPQST
     QEVITSSLLT FADIRQLQQR NISLVEASRE LAARLEVLER ERSDASELRV KLESATSELQ
     LARSAEKQHR DLLKVASQQR DMYKLLLESA RNSSADPAAA AASVPMETDQ QQQQQQPQTT
     AASTTLATSG VASDALSSAH AELSKLRTEL SSRDRQRATE LNSARAQLLE AQRASARLSS
     KLETAQRRAE LGEGGCARYR REIDILREMN EKYTGMLAKH EQEAVRLQSQ LIERGQSVTR
     LEAQLELAKQ QAKALRASES RLTVECEQLR QDRLRQGLLM TSLQAVQVNL EKRDQEVRQA
     AEARISAAAE RTASLERRLA EAESALAAER SAAEAAAASA ARQLAESAER LAAAVSRAKA
     AEERAAALVA SSTSSSAGQQ QSAVEQSEAA DKAESSQPED DDQEKSSAIA AYKEELAELR
     ERLKAMERDC ELLRGQAENY RAMAEGAEAR LTQEAEEHQT AVGEFEARLR ERQESIDYYR
     LERERQTLVS DRFKQTEEAH AMNADLRKQL HDRQQELQAA VERRDAAVSA EDRAKARATA
     EAAKAAEAAD KYQQELLLHA ADAKAMQAIR AQLAEAEKTC AEAREETRKS RADYEKRIAA
     LTAEAQRLRA SKTEAETRLT QLAAEFSD
//