ID   A0A1I8HIG5_9PLAT        Unreviewed;       294 AA.
AC   A0A1I8HIG5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=SH2 domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0006473-snap-gene-0.7-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0006473-snap-gene-0.7-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0006473-snap-gene-0.7-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8HIG5; -.
DR   WBParaSite; maker-uti_cns_0006473-snap-gene-0.7-mRNA-1; maker-uti_cns_0006473-snap-gene-0.7-mRNA-1; maker-uti_cns_0006473-snap-gene-0.7.
DR   Proteomes; UP000095280; Unplaced.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   Gene3D; 2.30.30.40; SH3 Domains; 1.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR19969:SF14; DREADLOCKS, ISOFORM B; 1.
DR   PANTHER; PTHR19969; SH2-SH3 ADAPTOR PROTEIN-RELATED; 1.
DR   Pfam; PF00017; SH2; 1.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SMART; SM00326; SH3; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   SUPFAM; SSF50044; SH3-domain; 1.
DR   PROSITE; PS50001; SH2; 1.
DR   PROSITE; PS50002; SH3; 1.
PE   4: Predicted;
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          71..133
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          187..288
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          8..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        140..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   294 AA;  32041 MW;  6A0900F03A5053A4 CRC64;
     APTVAAALAA APPASNIQSM SSPPGQQHSA SVPAPAGPLK MVPAVGEAPK STSAPIAGPA
     VPASTGSAGQ DAMFLVETLY RFTATHSEEM GFRENEILRV IATPADDPEW WLAKNSAGQS
     GLIPKNYVRV LPPSGTTGAA EVSRGYQDQQ SSPLPHHQQQ QQQPVRDPRQ QFIDADAEAQ
     GLANRPYYWG CISRGEADRM LMQMARPGEF IIRTGESNPS DLTLTMRARE KNRNFKIRRI
     PESNGLRYNI GQKYFNSLED LVKHYMEHPI FRSTDERCHL AGAFQHPSLS GSQL
//