ID   A0A1I8HIM4_9PLAT        Unreviewed;      1908 AA.
AC   A0A1I8HIM4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=NACHT domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0006205-snap-gene-0.3-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0006205-snap-gene-0.3-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0006205-snap-gene-0.3-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0006205-snap-gene-0.3-mRNA-1; maker-uti_cns_0006205-snap-gene-0.3-mRNA-1; maker-uti_cns_0006205-snap-gene-0.3.
DR   Proteomes; UP000095280; Unplaced.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR025139; DUF4062.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR19871; BETA TRANSDUCIN-RELATED PROTEIN; 1.
DR   PANTHER; PTHR19871:SF14; DUF4062 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF13271; DUF4062; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          408..547
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          1233..1265
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1553..1597
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1844..1891
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1237..1265
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1908 AA;  216128 MW;  90F358CBDF1D8299 CRC64;
     MWEGPNGSAQ LTAATRGQCV YLKVMKGRLD DLPIMNSRVV RIFLSSTFSD MGTERNYLMQ
     HVNPRLKKFC RDSFGLEFQT IDMRWGVGDE VQLDHQGPYM CYQEIDNSLI MSAGPYFICL
     LGQRYGNQPP AALVEVDVFN NIVEALKEDG RDVSCLHEWY TIDENNKPPI CVLRPIATLA
     EAADKELLKA ARQRWEAVQD SIIGLMKRGA ELCLQKTLIS HATMKKFTAS VTEMEVISGI
     LSKPPQKLAQ ALAFVREFSD LESQRDFSRG KMFKFIDLTD SVNEDGEAVK VLDEAVNAMV
     KELNRHVLTR MAGSNSFTYS LKWTNDAEGV GMSSHKDYLE KFGSDYCDNV KRLVAESVRE
     SMRLRSDDLY SEVLQHSTAC VNYVKKFQGR QEIIDKVKAY VQASNTTEPL VVYGDSGSGK
     TSLLGKAASL VRSWLPESDS KDAIVLLRFL GTSPGTSSIR QTLKYLCRQL AVFGNEDDQE
     KCESLDDFKE ILNTFYSMLE RMGQFRRILV FLDSVDQLDS SDGAYHLTWV RTPLPANVKM
     VVSTLPNMFD LLKTFKGKLP NPDIYVEVTP LETSLCTSIL SALLSEQGRT LNEQQWALVE
     QAFSKCSLPI YVHLLYHEVL RWRSYQQVDE SSLRYTVRQA IFQLFEKLEL KHGRLFTSHA
     LAFITASRNG LSESELEDLL SLDDAVLIDV FQHHLPPFIR IPPICWARLR HDIGSYLVER
     EADNIRVVFW YHRQFIEVAQ EYFLSDEKTR RDIHSIMADY FLGLWSGRRK KFVYPAYLRK
     KLNLPEFSME DRAVPEQPFV LRKDEDGTAQ YNLRKLNELP WHLIKSGRVN EFYDYIVFDY
     DFMFNKLKGT SRYLLLRDLD LPQKLGVEYI KEAELVYNAI RLSAQSLVYD PVNLSVDLIG
     RLIMYEKDCP RVKLLLNQCR QSKQALSNCC LIPKVQCFDS GSGVLYSSFD LGLGMGLVMP
     NGQLVSFSLI NNEVTWYDIE GNEIKRFSSD YNLFLSMKYM STGYIPDDCV MHVLSMRSKN
     AGVTEDDRQA LVLNMGRKKI QEEIEEYEAC NKDVPQELRD MMESLNAGEI PDSIMEKLDV
     DGMMKKMMSG EEEAQKSQDL VRVDFMNGRV TKLMTLDPSW SVSSDDVEYV TKDYVLCCKG
     KSDSTGTSTL RLLSLGEKKF VALYEENTSG TSRIGTQNLD SKNNLLCFGI EAGSNHSTLL
     VFMNLNTKEI VRGSLPDIFK SADKAELESM WRYSPLKQPD NKKEEKTPDE NCEKTEADES
     PAASEADLKS KAIELLQQAE EVSASSCLID HEGNIVAIES FDIKYSQNFV SPSRRRMTFL
     LKRKSRLYGQ TSVLRGLLYD CDEKRAVGMT ISPEQDKFKK AASSFGDGTQ AKFTEDERLL
     VTSGSKPKGT DFFTICHFPD ESAGDSDERM FIMTKVYNLK HFTDKLSHHS EEDALLPMYT
     QVKPCKNATG LTDCHTVDIR TNEALISLNT RTLVVKKSSS RDSKEDDQVE TLRLSDKPPI
     IELRRDPKAP FSVGISVISN QLVEKVFGST SKEELLQSRK SKSVGGVEFK FHVDAENEST
     KEKKDKKEET KEPSENQETK EENSTETKGD EEELTEAAKK AKEEKFLKKR LNNRNDLVDI
     QFLPEKCTLN LAFSQHLKAS EEIRVGVGVP PIWLGAVVRL DYSDVEKGTP TSEMQFQHSI
     GKVFDMGPAV AFLHDNQHLV NYKLQIVDYM KGEVIRCLSQ DEDLYFVRLQ ATPDCSLLVG
     QVYFPAYEVE FAVFDDESMN NSDMFAIVPP RGLQVYVISD GRRVANYLFE SDPFGLCLVG
     EDGRDLLVLT HNAPIMLFEL HDPQPLVAAD GAAQMHSMKA IDATANADSS VGSPAKAPGP
     RPEYLDMLTS TGQLNGRGSE REARGPDRVP GAVLLRYKAQ CDSQQPDI
//