ID A0A1I8HPU5_9PLAT Unreviewed; 491 AA.
AC A0A1I8HPU5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE SubName: Full=Rho GTPase-activating protein 1 {ECO:0000313|WBParaSite:maker-uti_cns_0007353-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0007353-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0007353-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I8HPU5; -.
DR WBParaSite; maker-uti_cns_0007353-snap-gene-0.2-mRNA-1; maker-uti_cns_0007353-snap-gene-0.2-mRNA-1; maker-uti_cns_0007353-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR45808; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR PANTHER; PTHR45808:SF2; RHO GTPASE-ACTIVATING PROTEIN 68F; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
FT DOMAIN 110..266
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 303..489
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..71
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 55588 MW; BBA4FD5F76FCF5F6 CRC64;
MASGPAAQSV PAEDNDSSEI GDDCEFDGAE AAGQEGGDFA EPELEFDESG LELTENEALE
TFEDYDEDDP SDENLGAGRI TPEGYIDEDF EDTLGSPATE VNTQDLVDTE FKEISRLGII
QVVGDDRLGR KVIIFSACRL PPAENLDHQR LLKYIINTLS QYVENDYVLV YFHHGLNSKN
KPSFAWLKQA YSEFDRKYKK NLKAFLIVHP TKLIKALYFL FKPFISVKFG RKLTYVNYLA
DLKSQNLYFD QLPIPQRVRE YDDSIQPASG NRAALTSQYS RSEDFAYGQQ LVANPLPTTQ
FGVSLQHIKH YNGGSVICPV VEHTIKYLRE CCLDVEGLFR RSCSVAQVQD VQEKYNRGEY
VDFRDLGNPH LAAVLLKTFL RELAEPLLTF ELYEAVIENH ALPAKTKVSH ARSLISQQLP
DDNYDLLNYV AQFLSEVADN STRNKMTALN LGIVFGPSLI WSRQQASLTV MKPINCFTQL
LILHYNHIFV R
//
