ID A0A1I8HQR5_9PLAT Unreviewed; 1064 AA.
AC A0A1I8HQR5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE SubName: Full=Importin N-terminal domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0007504-snap-gene-0.6-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0007504-snap-gene-0.6-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0007504-snap-gene-0.6-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR AlphaFoldDB; A0A1I8HQR5; -.
DR WBParaSite; maker-uti_cns_0007504-snap-gene-0.6-mRNA-1; maker-uti_cns_0007504-snap-gene-0.6-mRNA-1; maker-uti_cns_0007504-snap-gene-0.6.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 47..113
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1064 AA; 121773 MW; 057CDCF8F65F4CDC CRC64;
MPPVVMDAIS EEKVAKLLDF NHKLDIGLLD SVVTLMYSST GSQQQMAQQV LTTLKEHPDA
WTRVDSILEY SGNQQSKYYA LQILENLIKT RWKVLPREQC EGIKRYIVGL VIKTSSNPQM
LESEKVYLGK LNMILVQILK HEWPKNWPSF ISDIVGSSKS NESLCQNNMV ILKLLSEEVF
EFNSGQLTQV KARHLKDNMC AEFSLIFQLC QHVLDNSQNA PLVAATLETL LKFTHWIPLG
YLFQTKLIAT LVHKFLNVPM FRNVTLKCLT EIAGVQTSDY NDQFVQLFCL TTERLKEMLP
ISTNIREAYQ RGRDDEQNFI QNLSLFYCTF LREHASLVET SSALQGHFSD ALTYLVLISE
VDEVEIFKIC LEYWNSLCTE LYRENPFVSV LPEVGRPDRR RVYWPVLSSL RRIMISRMAK
PEEVLVVENE QGEVVREFMK DTDSVALYKS MRETLVYLTH LDPVETERVI TEKLLRQVDG
SEWSWKNLST LCWAVGSISG AMNEDDERRF IVVVIRELLG LCEHKQGKDN KAIVAANIMY
VVGQYPRFLR AHWRFLKTVV NKLFEFMHET HEGVQDMACD TFIKIANKCR RQFVQLQAGE
VTPFVEEILC NLSSIICDLQ PAQVHTFYEA LGMMIGAQPD RQQQDIMIEQ LFCLPNQVWD
GIIQMAAQNV ESLQEPDTVR QLSVLLRTNV SACRSLGHPY VRQLGRNFMD MLSLYKLLSE
DISKAVVAHG ELVAKQPLIR AMRGVKKETL RLLDCWVGRS TDPALVSDKF VPPLCEAVLL
DYQRNVASAR EPEVLALLAT IVSKLGEQAS QHVPPMLDAV FECTLEMLSQ DQHEFPEHRL
NLFTLLEAVT QSCFTTLIRL PTDRLRIVLE SVLWAVRHSL RSVSETGLSI VLRLLQKVDC
LDPAAAGQFH ANFFMSLLQH LFSVLTDPLQ AGQLSQVSSV LCLMFSLCER DRLHTQLQAS
VSNSEFVLQS LSALLSEAYP HLQRPQIAVF VQGCFSFNAD QKRFREHLRD FLVQIREFTG
EDLSDLYLEE QQEEIRRAQE AKLAQQCTVP GILNPHEVQD AMED
//
