ID A0A1I8HVX2_9PLAT Unreviewed; 260 AA.
AC A0A1I8HVX2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=CCHC-type domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0008117-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008117-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0008117-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the lin-28 family.
CC {ECO:0000256|ARBA:ARBA00008840}.
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DR AlphaFoldDB; A0A1I8HVX2; -.
DR WBParaSite; maker-uti_cns_0008117-snap-gene-0.2-mRNA-1; maker-uti_cns_0008117-snap-gene-0.2-mRNA-1; maker-uti_cns_0008117-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0010629; P:negative regulation of gene expression; IEA:UniProt.
DR CDD; cd04458; CSP_CDS; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 4.10.60.10; Zinc finger, CCHC-type; 1.
DR InterPro; IPR011129; CSD.
DR InterPro; IPR002059; CSP_DNA-bd.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR46109; PROTEIN LIN-28; 1.
DR PANTHER; PTHR46109:SF1; PROTEIN LIN-28 HOMOLOG; 1.
DR Pfam; PF00313; CSD; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR PRINTS; PR00050; COLDSHOCK.
DR SMART; SM00357; CSP; 1.
DR SMART; SM00343; ZnF_C2HC; 2.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF57756; Retrovirus zinc finger-like domains; 1.
DR PROSITE; PS51857; CSD_2; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00047};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00047}.
FT DOMAIN 129..190
FT /note="CSD"
FT /evidence="ECO:0000259|PROSITE:PS51857"
FT DOMAIN 236..250
FT /note="CCHC-type"
FT /evidence="ECO:0000259|PROSITE:PS50158"
SQ SEQUENCE 260 AA; 27971 MW; BFCA80FCAD43B5A5 CRC64;
IVDFTLGVVR SAMSVVDQKI QVWRRGAAVG VAGLWSPRLG RTLVGERQAP PIQNGERLTN
KGEPPTAVGT EQHSAVVSVE QLLSGISSSS QVLAVLDCQL RGGKASMTSG GQHPCGSNAP
GPSSSCVDRR LGRVKWFNVI KGFGFITPDD GGPEVFVHQM PGFRSLGDGE RVEFESRTTY
KGEEATLVCG PNGVDCVGSQ RRPAGRKKRR MRCYNCGQFS DHMAADCPSG PLPKSCYQCR
SMGHLVADCP LMKQQQQPQQ
//
