ID   A0A1I8HW62_9PLAT        Unreviewed;      1450 AA.
AC   A0A1I8HW62;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=TGc domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0008277-snap-gene-0.5-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008277-snap-gene-0.5-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0008277-snap-gene-0.5-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0008277-snap-gene-0.5-mRNA-1; maker-uti_cns_0008277-snap-gene-0.5-mRNA-1; maker-uti_cns_0008277-snap-gene-0.5.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0051017; P:actin filament bundle assembly; IEA:InterPro.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 4.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR039959; Fimbrin/Plastin.
DR   PANTHER; PTHR19961:SF18; FI19014P1; 1.
DR   PANTHER; PTHR19961; FIMBRIN/PLASTIN; 1.
DR   Pfam; PF00307; CH; 3.
DR   SMART; SM00033; CH; 3.
DR   SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR   PROSITE; PS50021; CH; 4.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           19..1450
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009320513"
FT   DOMAIN          955..1070
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          1101..1210
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          1234..1342
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   DOMAIN          1359..1450
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          821..850
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          864..957
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        864..890
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        914..947
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1450 AA;  162462 MW;  CF1CE9CAFB3A42EA CRC64;
     PVKGGCFVHL RAAALVRASC LRVWDSAMSL PPSLADLEYY RAYRPEDGEI DLASYLLDED
     NLAEKITSGF YPTPTVLAHL QRTLGEEPKD PDATDVGPFP SRRLKSDIFD AAKFAEKDEF
     VKSLRPEPLE SDAEFAVRLF ERSRCGLDSV RAAFCFVCCL PVDELAKAEV ESEFYTRVRR
     MRQTDDSYEI FNWLIGLTDV PSKKIFGYKK GAAFESGMEA RRSGGNWTAC YVEGEWRLID
     PLWGAEILTE FDTGNYSKLD DQGNVEDSRK SEGRLIYGCN EFYFLTDPEN LILTHFPVEE
     LRQWQLLDRP LTLAEFHRMP KFFSAALDEM FHYSINPSSH PLNVILGKPG TVKVYLREAA
     GQMYDYKAVV SIHKSNITDG TRAEIKQQAS INGYLSKTTR MSHDTVRFKF VPPCSGKFML
     SINLLRAIEY PDKILQIGIE YVSYVIHCPR ADRTAKMVPV GCANLMHFGA GAQLASARLK
     TDEPGEIKVE DGERLIQLES TDQRPHRLEC QLYGAADESI SPKNLLSWTV GPKTSIQFLS
     PDSGSFALVV RDRGIPVCQF LLDSASEFRD CRDFPLPDLD SLGGLDVADD AVQELVRPLS
     HPDPYILCND PSLQLKFASR ARLEIRAELS YICSNGESEE LSGYTFISRD SDGFIVDVRF
     KIAGHYVLQL FYRQSSSSPW QRYMNYFIRC VGQLDGRAEQ FPEPLPAWSS DNLLLHPTQK
     LLPLNKPVSV SVRIGDPDFK VAYLLNEGKN ERTVMQRDDV NIWQGTIEGL EDSAGSSVKL
     LGGPSENMCA ELLSYKFESE KDQTIRNKEI RSAAKLNLSR LGNERLRKRK QENHERKEMA
     LDPLPDAPRP EELADLQLEN ELEKLLLEDE PPLERRNRKH QKHEDEPALG EAQPEAPEDE
     PALGEAQPEA PEDEPALDAV RFETLEDEPP TMETKNETSE SKDEPGAEVS DQPAAGEKAA
     VADWLNKNLR SDPDCEKYLP IEDILAEIEG KFDDGILLCS AVNAVSQDTI DKRALHRDAG
     MNRSHQIENI TLALNSAQSL GVPVSSEAAE LAQSPKLLLD LLWQLIWFGL TDAVKQAAAA
     DSQKLKAMLP ETEQDADIRG IAPEQMLMRW VNYHLRNAGS ERSIENFSED VRDSEAYALL
     LQQICPPDIR DCLNPAAGIV AQSDLLLRAQ LVLQNADLIE AREFLQPEDI VSGNSNLNVM
     FVANLFKRWP CLPELPDGGQ AGAEQAAEKP PELVREERTY ANWMNSAGVQ PRINCLYTDA
     SSGLPYLQLL DQIRPGLVQW SRVSQTLRGA RAYFQRLENC DYAVELGRQL GFSLVGIRGK
     SLLDGDEMPT LALLRQLMLS HNPAAVSRGD SRVENSKRLV DENTIVEWTN EQLQRGGKKS
     RLRSFLDASL GNCHCLLDLI DCLRPGYVDY SLVLPGATEA QAVDQTGNKA SNLDSNNKLE
     AKELLEFCGS
//