ID   A0A1I8HWM2_9PLAT        Unreviewed;       639 AA.
AC   A0A1I8HWM2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=BTB domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0008424-snap-gene-0.7-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008424-snap-gene-0.7-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0008424-snap-gene-0.7-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8HWM2; -.
DR   WBParaSite; maker-uti_cns_0008424-snap-gene-0.7-mRNA-1; maker-uti_cns_0008424-snap-gene-0.7-mRNA-1; maker-uti_cns_0008424-snap-gene-0.7.
DR   Proteomes; UP000095280; Unplaced.
DR   Gene3D; 1.25.40.420; -; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR45632:SF3; KELCH-LIKE PROTEIN DIABLO; 1.
DR   PANTHER; PTHR45632; LD33804P; 1.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 6.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF50965; Galactose oxidase, central domain; 2.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          70..137
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          615..639
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..639
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   639 AA;  69061 MW;  C54BA6ADF4AE3B68 CRC64;
     FQLPMSGKVP SSSAEQQNAA LPGDLRPGAG SSSLSVAAAD LEDSVMFRDK RLFLVAFPSF
     ERIRRQGKLC DVTLRVAGSI FSAHRVVLAA SIPFFYGMFM HDMKECAKGE VEMQGIEANA
     LELLINFAYT GEVQITCENV QELFSGASYL QVPEVKDACV DFMRARLSVS NVAEVCRFAQ
     QFDCQPLVAE CQAYMTEHFT QLAATEEFKA LSLDELTGLL IRDEVHVGSE EEPERQSAAL
     AVLRCIRLTQ LPTGLLADIS KDPVFRNSLE CRDLLDDAKA YFLLPERRFG QLSSMRTQPR
     SCLSACGCIY AVGGLTSSGD SISTVECYDP GQKQWRVAEN MTTHRSRVGV AVLNGRLYAI
     GGYDGKDRLN TVELFDPGAG QWRRVAPMNC KRSALGAAAL IGKLYVCGGY DGVSSLRSCE
     VYWPERDQWH MMPNMADCRS AGGVVALDNQ LYALGGHNGL AIYDTVERLS PVDPVWRTVA
     PMRNRRCRHG VAALGDKIYV AGGYDGLHFL NTVEYYCPAT NEWTLAASLN ALRSRVALTA
     TWGKLYAIGG YNGVQNLSSV EVYDEESKVW AEAPPLTAHE GGVGVGVLPP RCGLAVSSSA
     PMLALARGSP VSAAATAPGS PAAGNSSNSS ANLETMAAL
//