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Database: UniProt
Entry: A0A1I8HXV4_9PLAT
LinkDB: A0A1I8HXV4_9PLAT
Original site: A0A1I8HXV4_9PLAT 
ID   A0A1I8HXV4_9PLAT        Unreviewed;      1102 AA.
AC   A0A1I8HXV4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|WBParaSite:maker-uti_cns_0008630-snap-gene-0.5-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Platyhelminthes; Rhabditophora; Macrostomorpha;
OC   Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008630-snap-gene-0.5-mRNA-1};
RN   [1] {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008630-snap-gene-0.5-mRNA-1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=26392545; DOI=10.1073/pnas.1516718112;
RA   Wasik K., Gurtowski J., Zhou X., Ramos O.M., Delas M.J.,
RA   Battistoni G., El Demerdash O., Falciatori I., Vizoso D.B.,
RA   Smith A.D., Ladurner P., Scharer L., McCombie W.R., Hannon G.J.,
RA   Schatz M.;
RT   "Genome and transcriptome of the regeneration-competent flatworm,
RT   Macrostomum lignano.";
RL   Proc. Natl. Acad. Sci. U.S.A. 112:12462-12467(2015).
RN   [2] {ECO:0000313|WBParaSite:maker-uti_cns_0008630-snap-gene-0.5-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0008630-snap-gene-0.5-mRNA-1; maker-uti_cns_0008630-snap-gene-0.5-mRNA-1; maker-uti_cns_0008630-snap-gene-0.5.
DR   Proteomes; UP000095280; Genome assembly.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095280};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095280};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN      129    183       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      320    369       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      373    433       MIR. {ECO:0000259|PROSITE:PS50919}.
SQ   SEQUENCE   1102 AA;  126363 MW;  E06B43022667727E CRC64;
     MTNASAGFIC IGDFISLYCE DTDGHAFSRN SSNAYNGLYV YHNLDRDHPI QVPDPQVLLF
     EVCIQNRYKL EKKYRKLANK PLAAPINSAA GANGNGDGGG GEGEHFEQAR SAALAESVDN
     MAEQKRNQGK RVRYGEIIQL KHVFTGKFVH VNTNETSQYD KNNMLLSLHE YNSKNAQFRI
     LPRYKVKSEG EYVQLLDQIS FESIKSPGHF CHASHGFPIE SGRIVSELNL GVDQTGFTIL
     KSHSHLAEFE VFARGGQFVQ LFHKELEAYV VAEGLFDDEV IEDVHLRIRE VDQLNPRTMH
     QSTSAITYWQ IESEKTMLNG EVLTWDQQFR FRHATTRKYL CVFQDSGELL VSLSEDATDP
     HTVFKMHPVL QETAELKFES YARIEHVITG SWLHAIKDKA YQRREFLNME DENSEVTCCS
     DRRYDDAYTI KKVAPAQVAD FNFVAGMVPF LQELIAMRRN GSAVACKDSY KICQALSELR
     SFMLDGAGEP RKARQKLLRN LRVIDLLVML LKIPLTGPLD EHHFGRVFSD AYDILHTYML
     GNSRKNALYF AKYIEFFQTQ MVDKSDLALK VTKMLVELMK DNRKIVDRIS KEQIDDFVNL
     LRKNEHYNYL KLLKVLCVCN GVAITDNQSY IAQKWLLEDT HGIYLTERGQ NIDRKPNETY
     VSTDQMKTWC PLVDFVQPDE NDQESVERCL FLRTQLDLFI ALCHGRNEEC IRLITKDLSY
     LTWEEAFLGL SSESLPQDFR AKYCEIIIGL FVNVGHNYSV VESPQLSFIY EYVGTKDSGG
     SSPAPDQYAA KDLITIFPVI RDWIAQFLDQ NRYMVASQMS NNLLIEKVLS LLHFLVKFGY
     YGGVDELAQL LPPLRNLLNG ESDVPFPPDK IGRDYSKDSK KLVQKFKHHE RYKRSPETLA
     IVRAKHAALR VLDLVMTFQE NARLASFVSK FKECEVSESS TKKKHIKPMV PALYESFDSL
     NTKRSAKSKQ NAIKKELRAM FDESSRFLDV DSLTGILIDL ANYEYDDMVQ LSLQLLNKLY
     SSKSTMFQQA INSLVLITPD SCRVHRELSK QVPLLRMMTR SKWTAEQALK MQTILGELCD
     LCHLPKAEEE PHPMNQRLMI SH
//
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