ID   A0A1I8HZH7_9PLAT        Unreviewed;       637 AA.
AC   A0A1I8HZH7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=All-trans-retinol 13,14-reductase {ECO:0000313|WBParaSite:maker-uti_cns_0008952-snap-gene-0.6-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0008952-snap-gene-0.6-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0008952-snap-gene-0.6-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the carotenoid/retinoid oxidoreductase family.
CC       CrtISO subfamily. {ECO:0000256|ARBA:ARBA00005855}.
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DR   AlphaFoldDB; A0A1I8HZH7; -.
DR   WBParaSite; maker-uti_cns_0008952-snap-gene-0.6-mRNA-1; maker-uti_cns_0008952-snap-gene-0.6-mRNA-1; maker-uti_cns_0008952-snap-gene-0.6.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR46091; BLR7054 PROTEIN; 1.
DR   PANTHER; PTHR46091:SF3; BLR7054 PROTEIN; 1.
DR   Pfam; PF13450; NAD_binding_8; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   637 AA;  69539 MW;  76CC6FF96ADF8FF4 CRC64;
     MALFGISISM WLVGVIGLSL YIVLYVISIT IYGKKPGRNP FVLPSLLVKK PERTADDVIN
     NQSARDSVLR QNFTGSRIPE RLDAIVIGSG IGGLTAATLL ARARKRVLVL EQHDVIGGCC
     HTFVDKGYEF DVGIHYIGEM RPGSFVRCLA DQLTDGKLMW QPLDVDFDRV IVGCVDGGGK
     NRSVLVTGDR KEFAKRLAQE WPDDAAGIEA FFSLLDRLKR GSKLYWGLKL LPLPLARLLI
     KSGLCGLFSA YFRYLHISLK QYLDQHISSE SLKSTLAYCF GDYGTPPGET SVVLHALLLN
     HFLRQGGFYP IGGPSEISFC SVPVIEKAGG RALVRAPVSS MVCNETTGRA VGVTVQRSDG
     EYTVLAPLII SDAGLINTAK LLPQTALEKS RIPRTLTDCQ LRSGHGAMSV FIGLRLPPGR
     CASTDPAFDD IRGRNLWLLS PSDSSAAETV DLQSIVNAYL SLDPQEAAAA DPPLLFASFP
     SLKDPSWPRR RGDDRLTCAI VTFANWDWFS QYQEGRSGHR GRDYNELKNA IGRRMWELVK
     CQVPAVADLE VELFQGKLPD PPGRLAPDSC AQLRPEMGPR GLLLTGQDVA ICGFVGGMMG
     GLLCASAALN RNLIADLAKL IQADAKGILR RERPKAE
//