ID   A0A1I8I2C5_9PLAT        Unreviewed;       490 AA.
AC   A0A1I8I2C5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=VWFA domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0009353-snap-gene-0.3-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0009353-snap-gene-0.3-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0009353-snap-gene-0.3-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8I2C5; -.
DR   WBParaSite; maker-uti_cns_0009353-snap-gene-0.3-mRNA-1; maker-uti_cns_0009353-snap-gene-0.3-mRNA-1; maker-uti_cns_0009353-snap-gene-0.3.
DR   Proteomes; UP000095280; Unplaced.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   PANTHER; PTHR14905:SF7; HET-C DOMAIN PROTEIN HETC (AFU_ORTHOLOGUE AFUA_2G15840); 1.
DR   PANTHER; PTHR14905; NG37; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 2.
DR   SUPFAM; SSF53300; vWA-like; 2.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..490
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009320640"
FT   DOMAIN          64..228
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|SMART:SM00327"
FT   DOMAIN          290..449
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|SMART:SM00327"
SQ   SEQUENCE   490 AA;  55200 MW;  6094934AB0D6FD05 CRC64;
     MKLKEIFLAA VLVLVCINIA ESHKSCCCKP HPRRCPSGYR SVLVNRVVCK YRRRGRCPRP
     RPILGSLGFV IDDTGSMRDD ISGVKSRISY ILARNRLFRD FVVARFSDPY RRRVLRSSRS
     TAVRNYINAI KPSGGGDCPE YSLSAIRDAA KAARPNSMLY LFTDASAKDA RLKASVAALL
     RRKRTRLYVV RSGRLCGSSY KGEYDYLAKR SGGGVIRLRN KKNVKYVLKY IGLASAGRVP
     FRLPSSVKKL RRIRPGHCPR VYCPRGYRRV VKRRRICKGG PRPPPRPRRL GSLGFVIDVT
     GSMKTEIRAV RSSISSVIAA NRRFRNYVLA TFSDPYKRKV VAVKRKSSAL KFLRAIRPNG
     GGDCPEYSLS GVRDAARRAL SRSVLFLFTD ASAKDARLKK RKKIRLFVVK TGKLCGRAYK
     REYDYLARVS GGKVITLPSK SGVSSVMNFM KLAAAGKAKF SALPKTLKKL KKFRPRGRRC
     FTQILITCRR
//