ID A0A1I8I366_9PLAT Unreviewed; 3147 AA.
AC A0A1I8I366;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0009460-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0009460-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0009460-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR WBParaSite; maker-uti_cns_0009460-snap-gene-0.2-mRNA-1; maker-uti_cns_0009460-snap-gene-0.2-mRNA-1; maker-uti_cns_0009460-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR CDD; cd04508; Tudor_SF; 1.
DR CDD; cd00198; vWFA; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR032770; DUF4537.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR46785; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR PANTHER; PTHR46785:SF1; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 3B; 1.
DR Pfam; PF15057; DUF4537; 3.
DR Pfam; PF13768; VWA_3; 2.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
FT DOMAIN 1454..1581
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13768"
FT DOMAIN 1798..1866
FT /note="VWFA"
FT /evidence="ECO:0000259|Pfam:PF13768"
FT DOMAIN 2533..2658
FT /note="DUF4537"
FT /evidence="ECO:0000259|Pfam:PF15057"
FT DOMAIN 2899..3014
FT /note="DUF4537"
FT /evidence="ECO:0000259|Pfam:PF15057"
FT DOMAIN 3024..3140
FT /note="DUF4537"
FT /evidence="ECO:0000259|Pfam:PF15057"
FT REGION 540..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1984..2036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2062..2092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2273..2529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2668..2702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2709..2728
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2740..2899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..894
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2008..2022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2273..2337
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2345..2360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2434..2448
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2476..2491
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2670..2702
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2753..2767
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2768..2812
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2819..2833
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2834..2889
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3147 AA; 353309 MW; 71B3D7A5333F26A7 CRC64;
PLVHGPSAPL ASAPLRASGR FTPHASGLSA PLAASRLTPL APRLWPHRAS GLSAPLAASR
LTPLASPRLW PLRASGSFTP HASGLSAPLA SPRLWPHRAS GLSAPLAASR LTPLASPRLW
LTSHASGLTA PLASLRSGLT APLASPRLWP HRASGLTAPL ASPCLWPLRA SGLSAPLASP
RLWPHRASGL TVPLASPRLW PLRASGLTAS GLTAPLASPR LWPHRASGLT RLWPLRASGL
TRLCASPPLA SPRLAKLLAY SYFLLACSRN RYACIVFSNC AQFLANLMDK HGGRLAEVQR
RCFHGNNATW FEFGLPPGRG SVSVWHIWQA ASVIRTADRL AVRLPRKRLA ATSNDSRDSL
IFAALFELSN DTSGEAVRSR IQTERSKEIY LELMELQLSE RDQDEQHLLR VVIREVLDDV
HLFDSSAEDV SGDQFDFVIE KRIAGCVIIQ EGARHQRGRQ DAVGRILEAI GLVANLRNVR
DGARVPLKRL KAKANTTKIC WTTGLMHSVE VKQNWLRRLL YTCSHTAAVC RSRNQPIRTQ
ARMAAARRPN RQPSSGRLAP ARRPRVSGSA SVRRSAAATA NSTAESGCHG DDKPSFAKRP
AGSSRALIAV AAVASTTGRG EKRLDSADSV KLLTAAAAEA ARWIRRFQQG ADQGAARVQM
RAVAHGIAEK PARIRPVGWS LADSASTIGI GGLPDGQAVG QLVCRLGVAR INGAVDDRES
GETATEQRGG ESGAGAAVDA SRRRRAVPRL LRMRRLQNAV LPCRGLFCFG GFFLTLKWKE
LCDKRPRRQH QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH
QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH QRRQHQRRQH HQQLRPRNQQ
LIKCILQHRL VLHRGCQLRH RCVIIIIVLT VAASSSSWML ACRGTGGSSG RVIWLGCQSG
VFVSGGHYRG AGCRGGESFA ARQQLILLAG GATAAGVVST AARPAVAALL GVFESGGVDY
GVDVGGLMLK DTNCSEWDQE SNPRPSSPVT IRFENGAKSY RQQSVCLHGG SSRSSQFNSP
HLPLAVPAVR TLADPPPPLD AAARFGLATP TPTPPPTFMG RRDAADEAEA LLLDPEPGVP
PGDEPILVEE VDAEAAVGVP GGLDRGVSGV RLTGGSGFAP RRPAPPEVAV EDVAEDADEV
AAVLARFNFC REPVRRCRLR RRLTAQLGDF VLGMRRRPRL CRRRLLDPRS WSLAEAVETP
AGGTAPAFHV SKQQQQSQDG GSIREVVSGR GGSDIVQTSE KYNVDVPKPG ERWEIDVRDL
IPSDSWLAKY GLKKNRLDAH SIAAQLGFQH LTEFDSVLKK PISSRYGDNL FQRLLRDDGK
VYNITAGKEK LKQVEQRLLH AVRMYRRRME WLTSESRRIF GVIYEHSVCI ILDIKNMSPR
AFDTYLCAAE RVLKEQIIHK AKFNLIRCAD EVQYFSTRCQ PVTRETVQNA IDWLWQLDRL
APTSPTDTVE GVIRAAADPD IEAIYLFTEG SSSDASREIL IDKVKSCSEV PFHVVAYNCQ
SSDTLRFLRG VCELTGGRFH CYSITMEVDS FEGLPLDPET NKANIVLKRK LYGGVPAGGG
IRADVFKVFE ELEEARNLLA QVQHVLANTP DPQASKESPV ERDTVTAHER KEEYMKSSEW
LQRFGIVAKK LDFFDILAGV SFRHCDGVVN VMRAPDGNPE AREKAGALIQ PKLINARYCD
RFAHVLGKDG TVLHVQVTPE LHRIYEERMN VCLESIQRRI DWLREGSREL FGTIVEDQVY
FLIDTSASME PSIGFVKDKL YILIQEQLRH KLRVNFVAFN TKAYPWKDRL VEVTEQSLQT
AWNWIKFALS DRQTHAVYLL TDGRPDQPFK TVLSQAQLHN RLPIHTISFN CRDREANQFL
FQLARDTGAR FHIFSDQAND GGPESWESED IRLLREEYEL GKGYLDRVAA LRDECHRLAW
KRETAADSPE GAVARSTPRC LDRPQSAPNR VQKKTPRSAR QTTGKRGGAM VQPPAQPLLA
INADRSEDWV LPETREMLAR QRERDALRQQ EHQRQQHRQR NKEMLREENM SSKQWLKRHG
LAAQRMTILD ALSPTIVQHR PKYVPILNRM VLARVFDDIM PIAYASPRNR HSIQLVNPAA
VDLKAYKAKL RKLVEKYNKR LDSLILSSLT KEQLDELSKQ CDGEERPDFD SNKAAFYQAL
EQARWPVSES DVFLLEKEVE KARLYLQQAD DLQRVSSGKE TPESTREILS EIQRSQDDHQ
GSYEVSGRPD GDADKSGKEK NSKKRSKKRE PSPVESKRDS ERDSKRDSRR DSLRSGSERI
GRSQANSDKV SDKRADYRSR SPSRSPNNSP VHSTGFGELV DERELSHDSS KVNSSSRSGV
AEAAEPTEAF NNKESTVSAT LTERAEEKPE QETAVSADQS SQQEALKESE QAADSDRASS
HLSKESAVSC RPPKMPQKQQ PKQQQKQQQK LGKQKSKPKQ SKKNPKTAAA PGNSASEAQQ
REAERRALDS LRGQRVIARN EEDGLYYAGL VECCPDMRTA RIRYDELPKS GSLVPTRFCI
PICGALSYPI LRTNDTVLAQ VRNLKNRVVC FAPARVLVPP KDESRGQKFY CVRLYNGKKC
ECTRSSLIKI GETRYTFLTR ALLSKCRGED STAQGDEGDD YQRRQREPSN ERDGEQETEP
LRREIRRLRR QLGQMQSTQD SESRGAQERI RNLERQIQQL QAENNQASER SRRGEHRRRR
HHSGGGYRRS RKDSLGDEDD AGIDRDGHQF EEIDRSRDRD GGGKDETRGG SASDRPPQRL
EFRPTDEETS SELARLASRQ SEQDAVQPDD SVSQQGRQAA LDSGRQRQRQ RQLQQRAQPS
SQQQPQRSAR RDTSELKPGE EVLARWSDDG WYYRCIVVGP AAPEEEEGVA DDAGEDGRRY
VVEDGSGQSI THGSTVVALH PAYSYSYAPG VVVGHDSGTM WVTVRFYDGS EVRLPRQECY
AIDAGQFEYS VEYIIHREKL WVDKSVVARV NRTGCYLPAT VKNRVGSGRQ YVVEFSDGHQ
AVQALEFIFG GLSRRCSLHE GDRVLAQIAK NIIFLPGWVM SVNSDSTVNI KFVDGSSSRN
VKQLSCYWLT KEFFDNAVSY WRSRHNP
//
