ID   A0A1I8I3J5_9PLAT        Unreviewed;      1639 AA.
AC   A0A1I8I3J5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=NACHT domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0009634-snap-gene-0.12-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0009634-snap-gene-0.12-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0009634-snap-gene-0.12-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   WBParaSite; maker-uti_cns_0009634-snap-gene-0.12-mRNA-1; maker-uti_cns_0009634-snap-gene-0.12-mRNA-1; maker-uti_cns_0009634-snap-gene-0.12.
DR   Proteomes; UP000095280; Unplaced.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR025139; DUF4062.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR19871; BETA TRANSDUCIN-RELATED PROTEIN; 1.
DR   PANTHER; PTHR19871:SF14; DUF4062 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF13271; DUF4062; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          69..157
FT                   /note="DUF4062"
FT                   /evidence="ECO:0000259|Pfam:PF13271"
FT   DOMAIN          381..521
FT                   /note="Orc1-like AAA ATPase"
FT                   /evidence="ECO:0000259|Pfam:PF13191"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1639 AA;  185410 MW;  3A483D7761B9FB24 CRC64;
     MKRLARPPKT NPKAPQLRSP NGNPARRFKA AAVMAPMFIS EEQSRENLYR RLLCGNLDEL
     PKKDTKSIRI FISSTFSDMA VERNALMKTV YSKMKEFYRD QYGLEFQIVD MRWGIQDAAS
     SDHKASEMCF NEILNCQRLS SGPHFMTILS HRYGGKEAPN RLTEEEAGIL EAAMSDRPDD
     LALLHRWYLR DENGRPPVYN LRPLESEAEQ TDWPHDGPAL QKALEVAANA AVAKGSMTSA
     RGYPVLYIQM GVLDAHPELK PFAFAIFRDI TDIQQRLDEG DKAAQRFADP EAAEALDGLR
     SRLRDLLPKG VTEYSLTWQP PKGISPEVHA DYLDSVVKDF EMQVRRLVDT FRQRRSELQA
     DPLYAEVLQH AHHCVRYVTN FQGRKEFLDQ LRDYTTGDSR QPLLLCGSSG CGKTSIMAKA
     AKSARSWLPP DNQPSALLLL RFLGTSPSTS SIRQTVKQLC QQLAVFLGST EAQQVAGMDS
     FQELVSTFYD FLQQLGKSRR VIIVLDSLDQ LDASDYAYQL TWLRSELPPG CKMILSCLPT
     LHGIRENFLQ LLPDRVMDVP PLEPALCEEI TRARLEKSKR RLTEPQWDAL RTAFASCSLP
     IYIGLVFRQA RRWSSYTPLD KTVLEPTVEG AIRLLLSQLG TRYGEVLVRN ALSYVTASRT
     GLSEAEIEDL LSLDDDVLRE VFTHHLPPFI RVPPLAWTRI RQQIDDYLVE READGVTVLF
     WYHRQFWEVA QKLYLSDPEH NRIIHSRMAD YFFGEWAAGR EKPFECPERV KAKLERDGLP
     VPMAADRQVP AQPFVLRVES DKPYYNLRRI NQLPRHFIRS GRVVDFLEHV AFNLDHLQSK
     LASSRRHQLL MDLHLFFDLK KKERGSEQNE LDLTRIYNAL RISAYSLSHS PLSLPVDLCG
     RLQPFAARSR RISDLLEACK KDSPLLLPVN NCLDTGSGYT HCTVQVRLSI GNLCEDGKIY
     AVSLQNNTVT WYDHEGSELK TVVSERPAAS HIRFVAVLPT SGCFCTVEEV APGQFQLLRA
     NMRTGAWKVL MPSLPDSLPL QYFAKSGSGC LEATEGHMIF AKTFYATMPI TYCLLKSEPL
     RHFLFRSWPM QLGQSLINDR CLFYIGHRIS EGEETSDEPL TPRVVDLDTF EETELDCSGQ
     GLAAHELTSE NTSFFDDGEC LFLVTLSPGG ALFTFYLFDL DPKVERRARH ELELEAAVNK
     PFMTSLSRTA SVAVVMLSEP LTVPVAYHRV LDKSYELDTN AEIHTVLNCP VHISDDGSLL
     LVKAKAYFTF NVWSAKDGSF LLALRGVSDY IMLGQPYGTD YLVINTMPEA GANASTVQLK
     VFNLNKLAGQ LSEFESNFVT KKEERRADFV FDPREQALWS GYFDKRLQGG VMYCTDLGGT
     GARDAKLREP LPDGKVDGYD AEVLAAMSRF KEAWNSKLNQ LCNFPDLQQH GLFLRLLPRY
     LLFVMRLASQ PTAPVSFEVP ESLQLPPEKD RSRSMRTLRD LLGNPDLHLA IVSHPAVRPF
     PVGYFMHGCD QPWLPATPPS VSAAIDGPRM HLLVRGPGNL QAPRLSDVLD GRSTESPDLS
     DYLLCLDLPG RKVQRIKTWP VPTVGDEFVG QARREVALQV FAEARQVCQY LVNSGKEKVH
     QYLPILQQFI ETLTARCRA
//