ID A0A1I8I3V2_9PLAT Unreviewed; 532 AA.
AC A0A1I8I3V2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Protein kinase domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0009549-snap-gene-0.3-mRNA-1};
GN ORFNames=BOX15_Mlig011660g3 {ECO:0000313|EMBL:PAA83854.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0009549-snap-gene-0.3-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0009549-snap-gene-0.3-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:PAA83854.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA83854.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA83854.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; NIVC01000401; PAA83854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1I8I3V2; -.
DR STRING; 282301.A0A1I8I3V2; -.
DR WBParaSite; maker-uti_cns_0009549-snap-gene-0.3-mRNA-1; maker-uti_cns_0009549-snap-gene-0.3-mRNA-1; maker-uti_cns_0009549-snap-gene-0.3.
DR Proteomes; UP000095280; Unplaced.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR PANTHER; PTHR48016; MAP KINASE KINASE KINASE SSK2-RELATED-RELATED; 1.
DR PANTHER; PTHR48016:SF29; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1A; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 268..528
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 233..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 297
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 532 AA; 59857 MW; 2580E78C411CAB64 CRC64;
MEDDSAVSDA LRGLEQDFER NLRLNEQQQA GLRVKCEFNG ESRVLNTFAR PLKLTDLRNE
LQARYKRRLD IYFTMPNGEI DVPVLSQDDL DLVVRIIDHH QNLRSLRLLL RVPPDAEDTT
DGNGRCSPPP GTLPPGAEFH DTASQMTAST YSEGEFIPED RDTDSLSSVS ESRQSLDTFQ
IRARGLGSRA SVHSDSAVAM DDMSRRGGPG GTFPRRNVVH IDDGRASVPR TMQRTRTPAE
VAAANRRDFP RADSLGSAQR SPAAPDNWKQ GDLLGQGAFG KVYKCHDQDS GRLFAMKVVQ
LDANQDPATS REVKALEIEI QTLKKFSHER IVQYLGYHQD AYRLCIFMEY MDCGSLRDEI
KRFGPIREIL ARKYTRMVLE GLSFLHRNTI VHRDIKGANI LKDSQGNVKL SDFGSAKHIK
TLQSAMSTTF AGTAPYIAPE VIRGKKYHYK ADIWSLGSTV VEFLTGHPPY HQLENAVSVI
YRIVSDQKVD YTLPSEVTET ARQFIDACFT HALEQRPDAD SLLRHRFCTE AL
//
