ID   A0A1I8I855_9PLAT        Unreviewed;      1725 AA.
AC   A0A1I8I855;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Choline kinase {ECO:0000313|WBParaSite:maker-uti_cns_0010743-snap-gene-0.13-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0010743-snap-gene-0.13-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0010743-snap-gene-0.13-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC   -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC   -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC       {ECO:0000256|ARBA:ARBA00038211}.
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DR   WBParaSite; maker-uti_cns_0010743-snap-gene-0.13-mRNA-1; maker-uti_cns_0010743-snap-gene-0.13-mRNA-1; maker-uti_cns_0010743-snap-gene-0.13.
DR   Proteomes; UP000095280; Unplaced.
DR   Gene3D; 3.90.1200.10; -; 3.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR   PANTHER; PTHR22603:SF93; RE24176P; 1.
DR   Pfam; PF01633; Choline_kinase; 2.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
FT   REGION          471..553
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          577..601
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          795..827
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1684..1712
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        471..497
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1725 AA;  185791 MW;  B75248E270A10B96 CRC64;
     MSQEQPLTKA QALSLCAQYL GGAWAAHVDS VRGGLSNYLF VASLADSVQP QAGQPNRVLI
     RVFGEILSNN AESVVLDSVI FALLSEKRMG PHLYGVFKGG RIEEFVANSA PLRCTAWEMP
     LSKEPRFVFK MMQSWLRSVE EVVSGKTDRE EPPPRPGFNA TPVARFLRDF RRRLLQSAEF
     AVVFCHNDLQ ENNILKFDNA SRQHGFSLQL IDFEYCSYNW RAFDIGNFFN EWTLDYTPSE
     WPYFSLSPRL LPQPGGPADL LALLPALVQR ARDRPQGAPV SPRRESSDCR DVAGADTVAD
     DVEVATAPET NNAVAGSEAD AALLLEAKYG ALMSHFFWSV WSLLQASVSS IHFDFKEYAQ
     LRFRLYAKLK EEITGKPSGL PVQRLSTPDS LSPPCHPLAV ESLAADGDRR HPPADSEFAE
     SAIDDGVEEV GPAAAKVAAA RDSSSRESAS LSRLRRLVRG RATSRCSVQC RSSIRSMSSG
     DAVSTETPFT STRRSPLRKP LSAPPAAPSS ATLSMAVRRR RRSSRRGLAR KTPPKPPLSP
     LTMPIAGLRP TGPEMASAAS EARWQAQLSG VAVNAPAVSE RAPVQPAADK SADGQQLHQR
     RSPPAAIGGF ELLLDQSRLA LKVALSAGQL ALGGELGAGP ARHQIVWSGG GWRRAAPVAD
     VGVVGVNGVV GVVGTLFVGV LSLCAERPHF ARCGRCARCC ARSMNPRSSD DGTKSPPMLW
     TCRRPPQPRR CVWPGQLRHN ELIAAPRAPT LALRCPQVAE GGAQHRVFAS TTRSRFSPNR
     CRLLCVAGRA GRWQLPPPPA RSGGSAARAR TARGSPPAGA ADRGNCRAGA PASRYRLPRL
     FVPVASVTAV LPGLLDDQRT VIRVQLAQLA ALCVPLRQDE LRRLTGRLGA VGGQQQLQHL
     ASGCPPGHEQ RLAVAARHQA GGVVDFHQAA GAHVHHQEAR LAAIAAFLKQ LWEQLGIIRE
     AAAAAASGIQ SEVVQAGVPG GHPVPGQHQP GQIPGSHARL DREFLRLGGA AGKAGLDSNP
     RRRRLFRCWH CRGVQREPEP FLANADSILT KMRCFVQHSA ACRFSSSKAS STAASNSCEC
     GIGLEVAEAG PSLSAHTASP RLSGSISEAS RRGLLRSISK GTASWKARLT GIVSTHFTTR
     LTMMRLVKIS SQAQRSAIAR YLGALSSRSA KAGLFSGSSI ASSDTLATMM LRWPMERFRR
     FQISFISFGS ARFFVVSELP SSPIRVLSMC RLALRAPGEF KFGANNQTDL GRSQLRGRLS
     EVGAGELGAE RRCGGVCARL LSLLDFLSGG VRLRRPGRPA TELVVRAQWR ILLLGTLASS
     WRCGDKLSRG RQAEFASEFE VCIEPVRLLP RRGRTESVRR SRQNRRRVLT CSSRDFKSKP
     LDVLELDNGA PWCSGFVLHK TKGSQSQLKA SCGDSAVPCE LGTPEPSPAQ SCRMLVPAVV
     AEAAVAASAS TAAAAAAAQS AGWVCIALWP NISERIVSSR WFTDSRTVTI TKHRELPVKC
     GCSRRHDNHV TSGADPIEPG GRVDSGPFAA RDAPVNVGFG RHRDLREALD CSRAADVSHE
     FQPLRSGAAS VGCSRRSKEI ANVFVVDLNR AHCEAELPAG AAAASPQHGG DGQTVDARVQ
     LIANHGTLWP LQQEPTSSVM APNTQALELS GPNTRSLALA PGTPRVRKRI LHLPATFNRP
     ALSSGRMRTK MRSLPRRSSG IARPPAAPSI PHEATELGVD NRHRC
//