ID   A0A1I8IFW5_9PLAT        Unreviewed;      1389 AA.
AC   A0A1I8IFW5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Glycosyltransferase family 32 protein {ECO:0000313|WBParaSite:maker-uti_cns_0012058-snap-gene-0.2-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0012058-snap-gene-0.2-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0012058-snap-gene-0.2-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   WBParaSite; maker-uti_cns_0012058-snap-gene-0.2-mRNA-1; maker-uti_cns_0012058-snap-gene-0.2-mRNA-1; maker-uti_cns_0012058-snap-gene-0.2.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006688; P:glycosphingolipid biosynthetic process; IEA:UniProt.
DR   GO; GO:0006673; P:inositol phosphoceramide metabolic process; IEA:UniProt.
DR   Gene3D; 3.90.550.20; -; 1.
DR   InterPro; IPR007577; GlycoTrfase_DXD_sugar-bd_CS.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   PANTHER; PTHR32385; MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE; 1.
DR   PANTHER; PTHR32385:SF15; MANNOSYL PHOSPHORYLINOSITOL CERAMIDE SYNTHASE CSH1-RELATED; 1.
DR   Pfam; PF04488; Gly_transf_sug; 1.
DR   SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          442..469
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          699..734
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        710..727
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1389 AA;  150529 MW;  000C61F63302D5DA CRC64;
     MLQERLLRFL SICVLLGIIV FSGLNQQFHI QRKNGSLTAV EPRNSSGGSS SDCGPIPRIL
     HYTFSSEHAY SNYKEFVSDC LALNPDWQVY LWRDADAERL IKDHYPDFAA KFASYRGDLQ
     KSDAIRYAVL HRFGGVYLDM DVKCLQPLFP RLKSYAAFVD RERWEQSINL FGMPLLMMNS
     AMGSAPGHPF FKYVLEKLKN MHGHIPLWTT GPKALTGIYY NWLSSQQAKQ ASAVKVLPSQ
     VFSGSVDQSN PGLWSPCKKY PPEFGSRTPS ETERHKLAAE LSGFDIDRPD THRGRDLRRM
     ACASLALTNW RHSLHDNRTV GLHMYLHLGY GFGASRRGPK LIVSQNVAVN RIVQVQAGGE
     HNVPLDQLAG RLEFLAQLIG SDDSGGVAGV LQQFQSTHLA HSYTTRMRAG RTLSGSRSGT
     RPSWNSHCSA WAELAVSITR SRASRSGSGS SRSMSVTGSR PPPPPRPSCL ADAAELDVDG
     GGDGLACCRR ASQTKQENRE ARWAGSSCSV MRTHWLLNSQ AAWPFRRTWS FWLTNSILRS
     TCQSEICKIA VLSGIETCLT PQSLAEVGAE AGTGEALVGE EAPSAFGQPR EQLRLLYIQL
     PSQTTHLVNF FKSHPVNRIE QRGGGGGGVS RPQQVSQLLG HLADGLAGRR VGKSGQFSPF
     KIVQHRSDAG LAAQRVGLWQ TAARGANDVA VADCAVGGGG DDGSGPSVSR RMRLPSSCSS
     TPTRRVPGSP GQGRMTMSWP GRGLQSGAMG YLFAQPLVLQ QAGQIGIHSR TAAGSAGRQA
     GLSDVGLKLD KLALPVPGHG LAAVLGEAAT KNFFNAQRPT AQQVEYHGVG DAKFRLELSG
     LAQCHVLQGA GVWHFGFAHH NNCASGVQAS AARPAGHLSV LARQQRAPLP AIMLHHILRS
     SFCSAVRLCT IVSMRCLYCC ETLPKVVKLL IGQRLNRRCV NNSGLAAQRL RYGVLSHHCF
     ARRGVRGHEY IVVLLQVANR VLLKRIQCET PGVRGIRHKS GHVGHRLARV DGHSPFELEN
     EGVGHLPQLA EPTATSGAAC RRHWQPAIRA ADVCRLRTLG TESGSSASAS ATATAPLLTW
     RSNPLLINFN YAANIEENLR IWHRPGVVGR CPGRRSGFGR GFIRSERHGA DRRLGDAGSG
     AAARPISGQA AAAKVPTDEQ LRAAFARGRL TEQQGGTGRL APFEGQMRRR TVAFVQAGQF
     STFAQQIGPV TARSHQAPEC LPSGAAVSVS VSVQAERHVA SAAGPSEKAA APLATGLVTR
     FRIVIVESHA SCCLEQEHLL LQLVDSVAPL SPAPVQLSLG RFNRGARLQL FGLQFFCRQA
     QIPRCRLSRP ALVSLGGALL LQRLASGSQQ LGHFAADGQL LVQALALTLV NLVAEQRGRR
     RRLLLERRL
//