ID A0A1I8IHH6_9PLAT Unreviewed; 1495 AA.
AC A0A1I8IHH6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=EGF-like domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0012544-snap-gene-0.3-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0012544-snap-gene-0.3-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0012544-snap-gene-0.3-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR WBParaSite; maker-uti_cns_0012544-snap-gene-0.3-mRNA-1; maker-uti_cns_0012544-snap-gene-0.3-mRNA-1; maker-uti_cns_0012544-snap-gene-0.3.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR CDD; cd00055; EGF_Lam; 2.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 8.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF9; PLATELET ENDOTHELIAL AGGREGATION RECEPTOR 1; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 3.
DR Pfam; PF00053; Laminin_EGF; 10.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 30.
DR SMART; SM00179; EGF_CA; 7.
DR SMART; SM00180; EGF_Lam; 18.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 4.
DR PROSITE; PS00022; EGF_1; 11.
DR PROSITE; PS01186; EGF_2; 5.
DR PROSITE; PS50026; EGF_3; 8.
DR PROSITE; PS01187; EGF_CA; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 233..275
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 371..411
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 518..553
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 705..735
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 748..779
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 787..822
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 830..865
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 966..1001
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 543..552
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 725..734
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 769..778
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 812..821
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 855..864
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 991..1000
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1495 AA; 157668 MW; E4D5AFBEF22C51BF CRC64;
CLPGTCANGG QCNLFRSSGG GSLLDPAEQP CICKHGFHGR YCEKDIDECK LRSGDCEGGE
CCNTPGSYYC KCPSGYFLAE DKKRCLDINE CVKNRGGCQY WCENTPGGYR CLCPPGLLLQ
PDLKSCSKGK FEKPTALTES TVSLLMMRNQ NPCEVDNGGC EHLCEVIRPG RHQCKCLSGY
TLASDQKKCQ AQNPCSVSNG GCQHECTNRN GKAECRCYSG FDVSPSDPRS CVDINECDKN
GGRGPCDHIC KNVHGAYSCE CNPGWQIGTD GHTCYRIEIE VHDPCQVSNG NCDHICGVNQ
FGAILCSCRT GFALQSDDKS CQDIDECAAG SHCCQHTCKN TVGSYQCSCN PGFRPVAPTG
GSGGPSCNCT DIDECQDRQG GCQQRCVNTA GSFACECLPG YRLLPDGRSC TGKQQEMLVY
RCFLSLLPWR IVCTLKVLQY LYICKPGTFG AACEFACASC RNGGACNMEQ NGCDCASGWT
GVICNITCPT VSELGSVASW LEECHISPVS PALSQGKFGK GCAQNCRCQN GGECDPATGA
CTCPPGVTGD RCQHGCPPGF YGVDCDRRCE SDCGGGGPGG GYCRRSDGVC VCPAGRFGDR
CSRTCPRDTW GPGCQRRCDC PSINADSCDP VTGRCRCKPG YKLPDCRARC EAGFYGLDCA
LVCRCPAGTK CDHRQGQCLA ECPPGRHGER CERQCLRGRW GPNCANKCQC QNGADCEPRT
GKCICQSGWF GDRCEQSCPR GRYGIDCMNE CQCSGSGSSC DPITGRCRCR AGYAGERCEK
GCPAGRWGEN CEQKCSCLNS ASCSPDTGEC HCAPGWRGTR CEDRCPAGSY GPGCKSICAC
RNGATCDHVS GACVCPPGWL GPTCSQPCPD GFYGRDCLQR CNCSSKSTVC DPTNGECACP
AGWQGSDCKQ PCPAGSWGPR CAHRCRCSRA GSAGPGNECA RDTGACACRP GYAGARCETR
CPAGRFGPDC RLACACLNGG VCSADSGVCR CPAGWRGRHC ELACPQGSWG PGSCSRACPA
QCPTDCDPTT GACRCPPGRL GPVCQLACPA GRELHERLPV SERRPVRTEQ RSVPLRSRLA
RTGVRAAMSL GPARSQLQPV VPLSGWPAVR PSNRSLPVRG RLDRPVLQPA VSRRHLWARL
RSACNCTASS GQLCDPATGQ CSCRPGRSGA NCSSPCPAGR FGPNCTQTCR CGAAGADCDP
ATGACHCPAG WHGAACKRPC PAGRYGVGCA SRCDCSGAGS GDACDPVSGA CRCPPGFRGA
RCSELCPTGW HGPLCSKPCR CGRDNSSEAV CDPITGECRC PAGLTGDRCQ NRCPSGLYGP
GCSVPCACAP GASCDHVTGV CSCPAGALPP DCSQPCPAGW FGAGCGRPCN CVASSSDACD
PVTGQCRCRP GYYGNRCELA CASGRWGRGC SRHCGSGCSH CNPIDGRCDC PLGWTGKSCE
KECPPGRYGA DCAHQCECAD GVPCQAQTGR CECPKHRIGS KCELSRENFF GLRHR
//
