ID   A0A1I8IJQ3_9PLAT        Unreviewed;       493 AA.
AC   A0A1I8IJQ3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   08-NOV-2023, entry version 25.
DE   SubName: Full=Rho-GAP domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0013449-snap-gene-0.4-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0013449-snap-gene-0.4-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0013449-snap-gene-0.4-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8IJQ3; -.
DR   WBParaSite; maker-uti_cns_0013449-snap-gene-0.4-mRNA-1; maker-uti_cns_0013449-snap-gene-0.4-mRNA-1; maker-uti_cns_0013449-snap-gene-0.4.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR   PANTHER; PTHR14130:SF14; RHO GTPASE-ACTIVATING PROTEIN 92B; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
FT   DOMAIN          80..296
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          305..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          395..417
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          468..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        324..356
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        468..485
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   493 AA;  53721 MW;  D92B88310980434B CRC64;
     ELQLEVSTRE NEERKERDSY IVQLNSLQGE KPAHCQQLLQ LMQARLDYHS ACARHLQQQL
     PKLQSEVARI TRLSGPCYGT PLGDHLFRTG RRIAYVIDVC TAALRRDDIM DEEGLFRVNG
     PTSSVQKLES FLDVMQAESE IHRYDSASIC GALKKYLKQL PEPLIGQSLL PEWKKACAFS
     SSDERRMALH SCCSELQRRQ PQYFDNLRHL IKFLALVCDR QERNKMSPKN LGICIGPNIV
     GTLAQQLQSA SSGATFPASA SGANGSGAPP NYDDLHSANL GTLIVENLIV HHDFCFGSEA
     PMGSLTNRSQ HHQQHHPFRR DSERSLGSTS FASSTAATSG AGHTEPGTPT NFDSAGAGGK
     FSTKSFHTDL YDTAFTLHAL RSNGVAAAAD AAATASSVNT EAHQHRPHPQ QHQHHRLDRS
     LGRLDRPLTT ATVPSSAAAT ATGTATHDFV KQARSIFEGH LLKSASLGAA TNSSSGNSPA
     GTNVDSPRLT RFK
//