ID A0A1I8ITR1_9PLAT Unreviewed; 413 AA.
AC A0A1I8ITR1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 03-MAY-2023, entry version 23.
DE SubName: Full=ETS domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0016108-snap-gene-0.2-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0016108-snap-gene-0.2-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0016108-snap-gene-0.2-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562}.
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DR AlphaFoldDB; A0A1I8ITR1; -.
DR WBParaSite; maker-uti_cns_0016108-snap-gene-0.2-mRNA-1; maker-uti_cns_0016108-snap-gene-0.2-mRNA-1; maker-uti_cns_0016108-snap-gene-0.2.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000418; Ets_dom.
DR InterPro; IPR046328; ETS_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11849:SF191; ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B; 1.
DR PANTHER; PTHR11849; ETS; 1.
DR Pfam; PF00178; Ets; 1.
DR SMART; SM00413; ETS; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00345; ETS_DOMAIN_1; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT DOMAIN 363..371
FT /note="ETS"
FT /evidence="ECO:0000259|PROSITE:PS00345"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 127..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 235..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..143
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 413 AA; 45706 MW; F12D2EB31C176EC3 CRC64;
MTSLDEFDFS ENGWEIPESG GVDISLLNES TQSFLDEMVK MEESTVSLIN DVNLSLDDWL
RQMPPLPSES PQSSPAALDE QQQSKAPSSA GSCLGLIDDD QTESEQDPED MIELDVKRIK
MSLEEGSLWH SAQQQQPPTS LGSRRRKLPS RPRQLRIQPI DVKLPSDDES ELASLVPSSP
TDSGVSGLSE FDASEMAAAV AGLVKPKPTY QLPHQLPHQP RQVVAGGLSW QQFIKTPTTP
DFPMPGAPTA SASAGRVGLL SKADDPPMQS AVQQPPRPQP SHTHTRIKTA HRVTRDQQLR
LETGGQCDDL VIMDTDSLRR HRMGESFAAH ATTKREHCTY SPFGEEVQLV CPKRRRDGGQ
TYLWEFLLDL LHNPTYSPRF IKWLDKERGV FKLVDSRAVS KLEPPTAAGL CEA
//
