ID A0A1I8IX43_9PLAT Unreviewed; 1680 AA.
AC A0A1I8IX43;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=EF-hand domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0017734-snap-gene-0.3-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0017734-snap-gene-0.3-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0017734-snap-gene-0.3-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR WBParaSite; maker-uti_cns_0017734-snap-gene-0.3-mRNA-1; maker-uti_cns_0017734-snap-gene-0.3-mRNA-1; maker-uti_cns_0017734-snap-gene-0.3.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 9.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR015070; EF_hand_DJBP.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR PANTHER; PTHR20875:SF2; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6; 1.
DR PANTHER; PTHR20875; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 6-RELATED; 1.
DR Pfam; PF08976; EF-hand_11; 2.
DR Pfam; PF13499; EF-hand_7; 2.
DR SMART; SM00054; EFh; 11.
DR SUPFAM; SSF47473; EF-hand; 6.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 7.
DR PROSITE; PS50096; IQ; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837}.
FT DOMAIN 578..613
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 796..831
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 832..867
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 944..979
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1052..1087
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1298..1326
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1414..1449
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 326..350
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1362..1399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1493..1512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1592..1649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..551
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1381..1399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1592..1614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1625..1649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1680 AA; 190299 MW; 8D5B8E527EFB0EC7 CRC64;
MPSVLMKSNS SIIAELIRLY LGPLRMNSAM IGLNRAFLQN QHSPDEILGK HEVLHVIGVL
LNAEGQQVKD VVQQLGRAIA VFQRRLIVRV GIKRLQQRGH RSVVEEAKEF RLLSRAALHV
VAQQHRRVVN KCKQDVGEGG AKLGAGFRVQ RGEAVQGLML HETLEEQSSL RNMVSSKRRS
ELFDLSRRQA NSIVMSLSSL LMSLSMLTLL TNRNEDSSEN WLSSNMLGVG RMQSWMYCTR
KVGLLDWQDF AMTRPIEQKL PVIGLDRLDR VVLQNADDVK DDVIFEHHLE YGLVVEEEDV
PDHLVQLAEA LAVVRLLGLG KEGRGEVTTF TRSPSQDSSQ GGSTRLSVAG GWPQADPVSL
SVSSPSSGLS SSTTSWAVSG WIRDSSRVEP SASDTTSRAM PFRDSTNTEL TWPVPLSSHW
RSSLSMYSLT RRRVAAPFSA MVTELSNDEV VYKTERATSL ARVVLPTGRN TAIIKLDNGV
YKKAHRDQMQ SFQSGGDKGT DSEQLVADGA SEIRSLENQS RCRSQSSTNG NLGEGASKEA
EGEKRKQADA TGLNGKKPID PNLNAGEIEK LLKNAIESNL SSVLRGFRLF DYNRDRKIQF
HELRKILEQY CFPMSNVQFE KLWNSIDYSK MGLIDYMDFL GRLGVTVPNA GSKNIGQRTE
RKKLQLGSSG MNMDQLEVEY RRRLKEQHGL LKKACLVVDS KHSGLMPIKN FKAILDEFVI
AVSDQEFSKL MERFSVKASH DIQWYGFLQK FVDPQSLSNG QTLPIRPSHK ANVVRGSHVE
ASVQDLIQLL YNHILSAYSS LRNAFLQIDI NRKGKITIAD FRRLVQGFKF ELSEVQIKEI
MVQLDPEHTG FITYQKFLDI FEEKESADGK VNYLEFLAVM QIDVYPGDVE GVSAQIASGN
EARLQMRQSQ HEKAMADIET HASLRTNMMS LEEIIVRLRD RSSQTRQHIR DAFLQMDDAR
KGFVSKAKFR LFLESHGIFL SDENFSQLTR ELEFGREGLD YMRFVKHFEG RDSELNPSYL
PMHNHKYNPV RGDEFGMSAQ VVENKLRSKI RENFTTLREA FHKMDSDGRG YLTKQDFRRL
LDQLMCLTND AEFNKLCKKL GIDDDCKLSY RDFLGKFQEK DDLATGHKWL VSNHRYNELG
DIKPKTAAEV HQLMAEKVHQ NYKDIARAFC HIDYLGRGYI TKREFKELLV RLNVTMNQEE
FKKLWAYYDT ANRNAITHDA FLKRVGVASA FSSGDGQGTS AKIIQNSAEY IAVHLEGQEN
RQENLVFNQA VLTVGLDADA LFIILQKRIR DFFPTTYAAF RALDVKEKGY LSQEDFRIAV
HQMHLFVRDE SFAELMRRIG LSQPTAQMTY EAFCLAFDEK FSGPRESQRP KTAGPMLDGA
RGGQQQQQQQ QQQQPQQRQD AKAFLKRLRA SVVKDGEILE KVFRSMDTKQ EGRIGASDFR
RVVDGFCFKL TDAQFKEVVK GLLSQGDQVD YYRFLANFSQ TQEAAERREW MEAANGGGGG
AGGSAEDGES LSQQEVEARV SEFVSARPYL LAQAFAEADY AQLGVLAKTD FRDILFRLVM
RMSNEQFDQL MTRVPTNEYG NVDYKEFLSR FASAEQPQQQ QQQQQQQQQP TAGGDARPDS
PISLTPPASA DQAQQQQPQQ PTLSLDTEAE AQLRRAMSQS WKSLFSRFKM LDQATPDKPK
//
