ID   A0A1I8IYU1_9PLAT        Unreviewed;       883 AA.
AC   A0A1I8IYU1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=AA_TRNA_LIGASE_II domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0019032-snap-gene-0.1-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0019032-snap-gene-0.1-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0019032-snap-gene-0.1-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A1I8IYU1; -.
DR   WBParaSite; maker-uti_cns_0019032-snap-gene-0.1-mRNA-1; maker-uti_cns_0019032-snap-gene-0.1-mRNA-1; maker-uti_cns_0019032-snap-gene-0.1.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   CDD; cd04318; EcAsnRS_like_N; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR004364; Aa-tRNA-synt_II.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR002312; Asp/Asn-tRNA-synth_IIb.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004365; NA-bd_OB_tRNA.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22594:SF34; ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR22594; ASPARTYL/LYSYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   Pfam; PF00152; tRNA-synt_2; 1.
DR   Pfam; PF01336; tRNA_anti-codon; 1.
DR   PRINTS; PR01042; TRNASYNTHASP.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU01015}.
FT   DOMAIN          596..694
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
FT   REGION          54..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   883 AA;  97093 MW;  ADDF28F418A6B1A6 CRC64;
     NAIPISSWFS DSSDTALLAL LPVLDSLRFV NDETADRIAS FELAPKQQHA VSLAKQSRSC
     SRSPIGRQSE TGNANPNGTC SDRVDKQDAA YFDSYQCLEV HATMLADRVR TLAYRLALMR
     AYRLVYRRVG IDIGCGSGIL THFACEAGAR VVYGLEAAAG MCSVAREFLR ANGHLDSGKA
     VVIGCRAESL NELPCDGGRA EFLVSEWMGY CLLYENMLSS VLDARDRLLR EIDDGFEVQM
     FPNRARLFIA GYTCGDQPDA DNSSVLDEDM DSLGRLYGCN MTPIVDAIER QKRSRPSVAL
     VEDTSHLITD STTLFCLNLA SLTKSELASG QATSGKFQLD AIQCANLDAF CLWFDVEFPG
     SNTRLSTSPF SEPTHWQQTL VWLPRSVPVS IDSRLSGQVC LCPNRLNCRD LDIEVTLLPV
     GIKDGLVESL DDIDAAAIVW RRCFSGSSRR VCLKQTFIEH SSQLANCENR ADTQEGFEET
     GEVSLVGWVR SLRRQKKVSF IELGDGTTHK TLQIVVSPSE LLPADVSADT CLRVVGRLSA
     TDRAANGLEL RASSLAVTGP ADRASGLSFH HEQRPDTARQ SPHLRPRLAG FQAVCRLRAA
     LNRALRSALD ERHYLEVEAP VLTSNDCEGA GETFRLADSE SFFRSPVHLT VSSQLHLEAL
     ALGLSRVYCL GRAFRAEKSL TTYHLAEFSM LEAEATELDS TDALCNHVEW LLKTAVNCVI
     SQCPEDLSKL ANHEDSDSGN NLSAIENLLS KSFARLTFAD AVKALMEKTS EFKVPPTMGM
     SDLRREHELA LVQLCDNIPV FVTDFPVKSR PFYCAESSPG LSASFDLLLP GVGEVLGGSV
     RESDSTRLNQ SIKRHQLLES SVERLHWYLE LRRFGSAPHG GYG
//