ID A0A1I8J3C8_9PLAT Unreviewed; 1940 AA.
AC A0A1I8J3C8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=ANK_REP_REGION domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0045683-snap-gene-0.13-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0045683-snap-gene-0.13-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0045683-snap-gene-0.13-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR WBParaSite; maker-uti_cns_0045683-snap-gene-0.13-mRNA-1; maker-uti_cns_0045683-snap-gene-0.13-mRNA-1; maker-uti_cns_0045683-snap-gene-0.13.
DR Proteomes; UP000095280; Unplaced.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 3.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF16; CASKIN-1; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF12810; Gly_rich; 1.
DR Pfam; PF00536; SAM_1; 2.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00454; SAM; 2.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT REPEAT 1..31
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 32..64
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 65..97
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 334..397
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 629..692
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 710..775
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 393..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 466..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..939
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 955..977
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 997..1065
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..614
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 778..796
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 832..846
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..897
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 916..939
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1940 AA; 207062 MW; 249B68B54C0FFA33 CRC64;
MSALHQAAFT GSPQMLQVLL EHGGRVELQD SRGLTPLHVA SYQGHFDSVH LLLKWNSSIN
AVAAGGQTPL HLACQGGHYD VVKLLLCNNA DPMLRTEDGR TAFDAACEFG HFSIAQLLVS
MKSVTGLLYE DCHFFTAADD AKEGTKRQQH NLPSCLHLTA RNGHTDVLRL LLNQSGVNVN
RLTAQGTCLH LAVAHGHLDA ARLLLEIPPP LGPLRLDTVK LRLRTAAERA AQGVPAFVAG
RQSHSSGSSI GSLGNSVGGS NGSVFMPAAG GPAIVLPYRP PRSNSLSLSC YGSDSLPRGI
DPTLQNSNGQ TAKDLITRDT PHARELNQML SERLSAVEAV AVRDFCDLAD PKSIAFRCGE
RLTVLERAGD IWKGYVTSQG LSRAGYFPSS AVQIQASRHQ PEQRPPSGSN DASTGGRSLS
VGSTSHPPLP SHLQQAGTGY FNHQAGRHSE GLVPCAIPQL PISTQTSAAS TNSSDSAVVG
IGAPSPPGIS GGGSGNRNSA ASLDSGRSSS HTATSCDSRV AFALPPQSST ASNSRLASTS
TGAPVATSAA AGVSGGGVAG SAACTSTSRV GGSQDSGLGP RQSLVSTCSS GSLGSLPDDA
NSSVSSSTGD QLTIEPPYNP ADWHRAGLSS EQQLEKFLNA CQFGLYLDNF QEAGYDLATL
IRCTPEDLNA VGLTDPKHRK RLRQELVRLA NSLRLAALPD SIEEAAASAH PMDDVGQFCQ
RLGLSDCVAD CLRQQGFALV QDLANMAWED LEEIGVSKLG HQKKLMVAID RLKRPRSMQQ
QQHQQHQHRH TASSGTCTAT ADAIVQHTPD SSCAAPCSSA TQAAAAPHQL PVQQPNRTNH
QPPQSPHHRV GNKPIAKVVG QSSTETSDPP PPPPPPPPPP PPPPLPAKVP PPPPKRVTSM
LRSRDPSPMV QPQQPPQPQQ QQQQQQQLNH RQPSSRGGAY ENAGQIETAV RNLQLKRPPP
QSQTASVPAV GNSCSRSNSA ASVASIPFAN ENCGTVIRHK QQQQQQQQQQ QQLPNGSSPD
VNNGYHGNQH GNQHGNQQSI APGSTLLMPP SSLSSPTSTA TGASDCDDSF SNLDDICDML
SDLQSMLDKE LREKPLLTWL TKPILNARPN PMMKNAKINE LVFLQPVLAS TRLMGSGPWS
ATNAAIELLL DAPFVLEQCS AQRMLEQIFA LSLNHGAQAQ VAVGLGGRVI WAGVQVEKVV
RHLVEHGHID WCLPVVVLLQ LGSVRQQQFE IHSEQPSGSL SQSSATGPVK RRHKVFVCGS
RLSTLDLPAT ISKRLFQTSI WQSSKLFRLD GRCNTLVPSS SFSCELALPL MSCSSSLDTS
EELHLSSRDT WSELPSRTEW KNCAGFIQYS LIGVTGCYRI AAAGAKGGDN PIRNHAGGRG
ATVSGNFNLT AGTRLAVVVG QAGSSVNSSS SGKAGAGGGG GSFVYRTGDN YLLAAAGGGG
GASHAHSGGV GGNGGCDCLG TDGRRFEFDA LLPPLLTPFG AAPTANQRTC WAAASSGDAN
WAAARMEQSV VVWRCSVMLQ IVSRRLRLMM TLRRMLKLQP GIIKLLALSD NQLIVKPLLL
LSRSRSTISI ATRRSRLRRL AARFASRLLL LIIGRVIRTP TAAAAAASAA NQIRQRRRGH
HVALMLVLVM ILHSGCTPKI FVAHILQVLR YFRIAKFICW RLGLRVHRRR QSRRLRNAPR
GDGAHQELIR RLAAQTVYFQ RLGFEQMRIQ LPSSAEINIF GFGLPTTRQR NTTRWPSTAT
WSTGVSRNSG LKRTVKVAKA SLVPALFDAS QMYLPASVGA RLNTVNEPLL WENERDFTIC
PLSLRQLSVG AGSPTAAQLN VAFSPCILSK SDGATRNTGL DLTLMMADAE SWSPAIFLAR
QAYSPASDGP ARIMRKWPLS ITTMRPSSGT IDWPFLRQDT SGLGWPSGGS HSISMVEPVG
TDLLCGSERN LSFSLETSEE
//
