ID A0A1I8JIA7_9PLAT Unreviewed; 1104 AA.
AC A0A1I8JIA7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=FERM domain-containing protein {ECO:0000313|WBParaSite:maker-uti_cns_0047875-snap-gene-0.3-mRNA-1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0047875-snap-gene-0.3-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:maker-uti_cns_0047875-snap-gene-0.3-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR AlphaFoldDB; A0A1I8JIA7; -.
DR WBParaSite; maker-uti_cns_0047875-snap-gene-0.3-mRNA-1; maker-uti_cns_0047875-snap-gene-0.3-mRNA-1; maker-uti_cns_0047875-snap-gene-0.3.
DR Proteomes; UP000095280; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd01765; FERM_F0_F1; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.60.120.920; -; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF34; FERM DOMAIN CONTAINING 7; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF00622; SPRY; 2.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SMART; SM00449; SPRY; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50188; B302_SPRY; 2.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
FT DOMAIN 73..363
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT DOMAIN 455..670
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 679..868
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 625..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..983
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1059
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 942..962
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 963..980
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1028..1059
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 121870 MW; 51C416F5EFAECC0F CRC64;
MSDHGSATMQ SSTLPLDGRG ATGRNAEFES TMSKKDYYTL RDKGVPFYQS GTMQSQQSYN
TASRPAKPSG KLKPIEVVML DGSVHTFDVD PNGKPTDLFD EVCVALGLHE KEYFGLCFRD
SSQMFFWLNN EKKLGKQIGK NEWKLEFMVK FYPPDPENLR ENLTRYYMAL QIRQNLMAEL
LPCSFITYII LGSYVLQSEV GDFDPLDEKM NSLMYLNDCP FCPEEYRNNA ELAERVSELH
RTHQRMTPEE ADLHFLRNAK KLAMYGVDLH ESKDASGEEV LLGVYHGGVL VYRNNLRINR
FSWPKILKVS YKGSTLKVSI RTGDNERDPK SETLFEFKCA SSKLAKRLWR AVVEHHGFFR
LKSAEKPQKP HIPGTFKGKW GTGIRDSQND QSGAYQEVQV TPDMRKSFKK KDDAYNREAR
TGAGGAGTSG LTNDDTYAMS NRQGAGMGAP LLPPVNRREQ YDRRPELDVD RPIRWQMNPS
DADPYLAAGM DPVRCAGACP AGVRDWQGCR ADRGIRASAG GKWYYETAVR GDGPSDQPVE
ARVGWADGNA DLNLGRDNHG CGFGTDPAGR HAQKMLDGVS EQYGVQLMTG DIVGAYLDLD
NGTVTYAVNG KELGPAHQLP ADFFTPTGTA GGNRKSRGGD GPPGGPQAVY PAACLRDGAA
ADWNFGDDPS RPLAYPPGGA WRPVGLALAN QTSENPRSWR LNPHDTSGPG LQLGPDQLSA
QGQLGFGWQG VRANKGLKGS EGGRFYWEAE PLESGGLGRV GWTTESGLLD VGRDANGWGY
GADHEGFGLA GNQGKKLFDD EIEAYGEPYA KGDVIGCFFD FNNGELQFAK NGQPFGPAYT
GHARARVLLP TVAMRDQTLD VNLGQRPFRY PPGPDWTPVC LAPESSIQPS SRAGIMEASN
LPAVDQKYDM IRENKPQIRA PSPKPRGNAG GPEGQSVTVL ESRTEDVEKV ESQRRQQQAD
ATRKQQNEEL SVTTSEQVGE PEEEIVTYVD EHGNTVTKKI VRSKKTRQVI TSKVIETRGP
AVPEGDAASS EHLEKSSGAS NRKEIRPAQS GRRRDHAHVG DIIFEQTGLS RKDKIMDENV
NDFSTIDSRK GRAKSRRMRV DTKY
//
