ID   A0A1I8JJ26_9PLAT        Unreviewed;       359 AA.
AC   A0A1I8JJ26;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:maker-uti_cns_0047974-snap-gene-0.9-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:maker-uti_cns_0047974-snap-gene-0.9-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
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DR   AlphaFoldDB; A0A1I8JJ26; -.
DR   WBParaSite; maker-uti_cns_0047974-snap-gene-0.9-mRNA-1; maker-uti_cns_0047974-snap-gene-0.9-mRNA-1; maker-uti_cns_0047974-snap-gene-0.9.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR   Gene3D; 1.10.287.690; Helix hairpin bin; 1.
DR   InterPro; IPR004868; DNA-dir_DNA_pol_B_mt/vir.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   PANTHER; PTHR33568; DNA POLYMERASE; 1.
DR   PANTHER; PTHR33568:SF3; DNA-DIRECTED DNA POLYMERASE; 1.
DR   Pfam; PF03175; DNA_pol_B_2; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
FT   DOMAIN          43..205
FT                   /note="DNA-directed DNA polymerase family B
FT                   mitochondria/virus"
FT                   /evidence="ECO:0000259|Pfam:PF03175"
SQ   SEQUENCE   359 AA;  41192 MW;  BE909527E680F302 CRC64;
     SLCTRRCSRK THTRLATRCN IRRRKCSILT RWLATLALPK VTVLPPSDLH IPLLPYRVQK
     KLFFGLCRTC MEQQCGECCD HSDQQRALTG TWATPELRKA FQLGYRLQAV HALAYWTEKR
     TGLFSDYVST FLKLKAESSG SPGMSDEDKA AYIADFYAKE GVTLDKVEPN PGLRFVAKIF
     LNSLWGKFCQ RDDLTSTEIV SSYEDWLARL TDPNLKVKAC EPIGSEFMLL EYRHRYFNQR
     PFRVVYRHSE GQWEPPHGTS LGMWTDEVPA GSRMTDFDAA GARSQVLKCK GIRLTPEIRE
     RSDELRSALL HGGSLQLPQL QFRRDKASCT IHTINMDKTF QRVLTKRVYG ACSRPYGYK
//