ID   A0A1I8JS55_9PLAT        Unreviewed;       543 AA.
AC   A0A1I8JS55;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Rab3 GTPase-activating protein catalytic subunit {ECO:0000313|WBParaSite:snap_masked-unitig_41279-processed-gene-0.0-mRNA-1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|Proteomes:UP000095280, ECO:0000313|WBParaSite:snap_masked-unitig_41279-processed-gene-0.0-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:snap_masked-unitig_41279-processed-gene-0.0-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the CDC45 family.
CC       {ECO:0000256|ARBA:ARBA00010727}.
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DR   AlphaFoldDB; A0A1I8JS55; -.
DR   WBParaSite; snap_masked-unitig_41279-processed-gene-0.0-mRNA-1; snap_masked-unitig_41279-processed-gene-0.0-mRNA-1; snap_masked-unitig_41279-processed-gene-0.0.
DR   Proteomes; UP000095280; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   InterPro; IPR003874; CDC45.
DR   PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR   PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR   Pfam; PF02724; CDC45; 2.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT   REGION          488..543
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   543 AA;  58633 MW;  4ACC943881A6F118 CRC64;
     SQFGVLVNCG ATIDIWETLQ PPADFQFYVI DSHRPFHISN FYNQQQVHLL VSEGEEVTVP
     AYGVVFRDSD DENSDAEDAD EDADPDAATA ALSAAERRGA PARVAQPQER ALLEHEQFTY
     HGPTSSLLLL EQAFRTSRPS LSALWCAIVG HTWQLLSGRL DWDAYFEAVC GLQAHVTSWR
     NASSAASASA TTLESQLQET ISSPAELQFS RCLNLWLLRH WSLEDCMRCS PHTACALQLF
     GSRGRQRLLQ FLADAGIAPE RGPAAVRLHL QNGLENSFSR LAGKFKLDPE RLFLPTFTAK
     AAFRPALVAT DCALLCACHL TRGDFCAAID CVTIECSEGV CRDLGLVRDW LSGQVDRAGA
     GAAGPGSVVN LGPFLFVSLP EAGGRLRCTC WPAGAAGLRQ PRQDAAGRPG CPCWPPASCR
     VRRGPEFSTV FLGLPPVGAE DCRNVFRAAM LEAARGCRAL GEAEFDGHAV RAAPRGRQEF
     CRRAYRTPSG RCGRRSEPLQ CPAASPGREL SAPAGVADSA TPPPQPGPEQ PEKPAVQGLG
     FEP
//