ID A0A1I8JSS6_ANOAL Unreviewed; 376 AA.
AC A0A1I8JSS6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=mitogen-activated protein kinase kinase {ECO:0000256|ARBA:ARBA00038999};
DE EC=2.7.12.2 {ECO:0000256|ARBA:ARBA00038999};
OS Anopheles albimanus (New world malaria mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=7167 {ECO:0000313|EnsemblMetazoa:AALB015831-PA, ECO:0000313|Proteomes:UP000069272};
RN [1] {ECO:0000313|EnsemblMetazoa:AALB015831-PA}
RP IDENTIFICATION.
RC STRAIN=STECLA/ALBI9_A {ECO:0000313|EnsemblMetazoa:AALB015831-PA};
RG EnsemblMetazoa;
RL Submitted (AUG-2022) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. STE Ser/Thr
CC protein kinase family. MAP kinase kinase subfamily.
CC {ECO:0000256|ARBA:ARBA00038035}.
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DR AlphaFoldDB; A0A1I8JSS6; -.
DR STRING; 7167.A0A1I8JSS6; -.
DR EnsemblMetazoa; AALB015831-RA; AALB015831-PA; AALB015831.
DR VEuPathDB; VectorBase:AALB015831; -.
DR VEuPathDB; VectorBase:AALB20_030496; -.
DR OrthoDB; 2900742at2759; -.
DR Proteomes; UP000069272; Chromosome X.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48013; DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED; 1.
DR PANTHER; PTHR48013:SF11; LICORNE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU000304};
KW Kinase {ECO:0000256|RuleBase:RU000304};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU000304};
KW Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304};
KW Transferase {ECO:0000256|RuleBase:RU000304}.
FT DOMAIN 55..338
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 376 AA; 41672 MW; 9232FBDBE9E105B7 CRC64;
MASRRIKPGL KVKLDGPGSS NSAADNTDKS TPRNLDKRGT LTVGERSFVV EADHLRKLAD
LGRGAYGIVE KMLHQPSGTV MAVKRITVTS GIGVAGGGGG GGVQSQEQKR LLMDLDVSMR
ASDCRHTVQF YGALFREGDV WICMEVMDTS VDKFYPVVYK RPGRTIPEAI LARIALAIVR
ALHYLHTELR VIHRDVKPSN VLMNRHGDVK MCDFGISGYL VDSVAKTIDA GCKPYMAPER
IDPASCSRTA GYDIRSDVWS LGITMVEIAT GRFPYATWRT PFEQLKQVVT DEPPRLPKVT
TAGSEPFSDE FHNFIDQCLK KQYQDRANYE QLLAMDFVKR YDDDNTSGDT SEMARYICMI
LDESDAITDS SASQPE
//
