ID   A0A1I8JUS7_ANOFN        Unreviewed;       329 AA.
AC   A0A1I8JUS7;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2019, sequence version 2.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Sulfotransferase domain-containing protein {ECO:0000259|Pfam:PF00685};
OS   Anopheles funestus (African malaria mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=62324 {ECO:0000313|EnsemblMetazoa:AFUN016209-PA, ECO:0000313|Proteomes:UP000075900};
RN   [1] {ECO:0000313|Proteomes:UP000075900}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX   PubMed=21129198; DOI=10.1186/1756-3305-3-117;
RA   Sinka M.E., Bangs M.J., Manguin S., Coetzee M., Mbogo C.M., Hemingway J.,
RA   Patil A.P., Temperley W.H., Gething P.W., Kabaria C.W., Okara R.M.,
RA   Van Boeckel T., Godfray H.C., Harbach R.E., Hay S.I.;
RT   "The dominant Anopheles vectors of human malaria in Africa, Europe and the
RT   Middle East: occurrence data, distribution maps and bionomic precis.";
RL   Parasit. Vectors 3:117-117(2010).
RN   [2] {ECO:0000313|Proteomes:UP000075900}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=FUMOZ {ECO:0000313|Proteomes:UP000075900};
RX   PubMed=31157884; DOI=10.1093/gigascience/giz063;
RA   Ghurye J., Koren S., Small S.T., Redmond S., Howell P., Phillippy A.M.,
RA   Besansky N.J.;
RT   "A chromosome-scale assembly of the major African malaria vector Anopheles
RT   funestus.";
RL   Gigascience 8:0-0(2019).
RN   [3] {ECO:0000313|EnsemblMetazoa:AFUN016209-PA}
RP   IDENTIFICATION.
RC   STRAIN=FUMOZ {ECO:0000313|EnsemblMetazoa:AFUN016209-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC       {ECO:0000256|ARBA:ARBA00005771}.
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DR   AlphaFoldDB; A0A1I8JUS7; -.
DR   STRING; 62324.A0A1I8JUS7; -.
DR   EnsemblMetazoa; AFUN016209-RA; AFUN016209-PA; AFUN016209.
DR   VEuPathDB; VectorBase:AFUN016209; -.
DR   VEuPathDB; VectorBase:AFUN2_009809; -.
DR   OrthoDB; 979113at2759; -.
DR   Proteomes; UP000075900; Unassembled WGS sequence.
DR   GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR11783:SF180; GH11818P-RELATED; 1.
DR   PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          68..322
FT                   /note="Sulfotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00685"
SQ   SEQUENCE   329 AA;  38756 MW;  39D7874EB2B7F0DB CRC64;
     MASTSFTFTD VTKESVDWNV NSNNILVQLN DWTDYPLDVT LQPPAPMFVS AKYRNYAQQV
     RDFQVYEDDV WIVTFPKSGT TWTEEMVWLI NHDLDYETAR NVRLNTRSTF FEFGAIADRY
     PIDTINIASN RQRPRQIKSH LLLPLLPRQL WTVKPRIIYV ARNPKDVAVS YFHHCQNLVG
     YRGAKEDFFE DLLNGRVAFC PMIQHVLNFW SLRDEPNVLF LTYESMKRDL RGLLPKVCQF
     LNKSYNDTQL DELAVHLSFN AMKKNPATNK EETVRSALQL NHREGEHFEF MRKGIVGDYR
     NEMPEEYIRR FDQFVAEQTA GSDFKFDYD
//