ID A0A1I8M4I4_MUSDO Unreviewed; 2270 AA.
AC A0A1I8M4I4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=Probable helicase with zinc finger domain {ECO:0000313|RefSeq:XP_005175912.1, ECO:0000313|RefSeq:XP_019893893.1};
GN Name=101887992 {ECO:0000313|EnsemblMetazoa:MDOA001160-PA};
GN Synonyms=LOC101887992 {ECO:0000313|RefSeq:XP_005175912.1,
GN ECO:0000313|RefSeq:XP_019893893.1, ECO:0000313|RefSeq:XP_019893895.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA001160-PA};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA001160-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA001160-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005175912.1, ECO:0000313|RefSeq:XP_019893893.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005175912.1,
RC ECO:0000313|RefSeq:XP_019893893.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005175912.1; XM_005175855.3.
DR RefSeq; XP_019893893.1; XM_020038334.1.
DR RefSeq; XP_019893895.1; XM_020038336.1.
DR STRING; 7370.A0A1I8M4I4; -.
DR EnsemblMetazoa; MDOA001160-RA; MDOA001160-PA; MDOA001160.
DR GeneID; 101887992; -.
DR KEGG; mde:101887992; -.
DR VEuPathDB; VectorBase:MDOA001160; -.
DR eggNOG; KOG1804; Eukaryota.
DR OrthoDB; 5405202at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18077; DEXXQc_HELZ; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR049569; HELZ_DEAD-box_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF365; HELICASE WITH ZINC FINGER DOMAIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|RefSeq:XP_005175912.1,
KW ECO:0000313|RefSeq:XP_019893893.1};
KW Helicase {ECO:0000313|RefSeq:XP_005175912.1,
KW ECO:0000313|RefSeq:XP_019893893.1};
KW Hydrolase {ECO:0000313|RefSeq:XP_005175912.1,
KW ECO:0000313|RefSeq:XP_019893893.1};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Nucleotide-binding {ECO:0000313|RefSeq:XP_005175912.1,
KW ECO:0000313|RefSeq:XP_019893893.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 318..341
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 318..341
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 210..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 464..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1322..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1397..1571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1585..1665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1772..1791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1827..1866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2037..2071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2158..2185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 464..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..509
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1411..1429
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1436..1452
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1456..1571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1590..1604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1827..1845
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1846..1860
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2270 AA; 248275 MW; BAB7BAF7DEFF48A3 CRC64;
MKNNSTNLMA IMTDKEKQAH DLVRCRNWLR AATLYDEILA SAPTWNRVQK DRHIICLLGR
CECLYELGKY EPCLADARKL LSMISEQQPA DCLTSVSRTR KWQIHALCKL KKYVEAEKTL
KEWIAQFRFR KFNEICNVLE GYRLVVNMLY SYDKSEQKLM DLAFLDDKMA SLDNKLDNWA
SKSLALDKYS KHLCGAGGGV GATGATGSNT NIKGIKKREN PTPNGGGPLN NMSGLMLASL
GVSSASSNKT ATADDAAATS EDANSTTCSY CAITFSSRNE LRQHCQTEAH QNVIMSDEGR
DWKWRPPPRG FTLDSYSLCE SWTESQLCHY GNQCVEAHGQ DELNEWKERF EYRRMRLQKA
CEKELYGKSY TEQILEKWIQ STAPEKIMCE KVDGIEANCE QDLVTSISSK TSKREWVFVL
KTTGKTLKAV ALLQDAHRSH FALKSIKTPD TTYELDAKTN QEWMPQKLST SSSSTSTSSS
EKEESKKSTT DSNAESSSSS SSTCTTNSTP VEHHVTVEFH TEIYGTFRQA VCFDFGSEPI
LVRHLCVDVV PVSDAEKIEE IKRDIINSSA TRWDVSNTHL VKFETTIGTH MKTEGYLNDL
KHEKEMLERY PCPRAQTFTL TQSTILDKRL TQNNYRSRIH ELLYVEEIAR YEQIARFNLR
TKLNVTSNYI LTPAGMATST AKYSLSGELF ALMHLGKDVS EDTSAGRLIL SNCSSVYISV
VDEANLGVDK KRHVYEAVIE DKGKNVIYLK LSSKCVEALK LKADTELHVD IQFQLNRLPY
CEWHHAVDKI TDFKIIFPAT EVEPNIPWTP KKQWSESCEP KLNAKQREAV NAITTTLSIK
LPPILLIGPF GTGKTYTLAQ AIKQLLTQPE AKILICTHSN SAADLYIKEY LHPWIEAGLE
EATPLRVYYH KRWVATVNSV VQKYCITDGA GNFRRPTVED IMKHRIVVVT LSISMELANL
DLPKGYFTHI FLDEAAQAME CEAIMPLALA NDSTRIVLAG DHMQMSPELF SAFAKERKLH
ISLLERLYDH YPSNFPCKIL LCENYRAHEA IIKFTSELFY EQKLIASGKQ PRHEKFYPLT
FFTTRGEDVQ DKNSTAFYNN SEVYEVVERV SELRKKWPSS WGKINDASIG IMTPYADQVF
RIRSELRKRR MGGISVERVL NVQGKQFRAI FLSTVRTRRT CLPIAGGSGV GGTAGGGGFP
GQSSSPSEDA DYGFLSNSKL LNTAITRAQS LVAVVGDPVA LCSIGRCRKV WERFIEICDE
NKSLFGITMW QLRSQLDGVE LKRGYVLNPL APEFIPRSLQ PEAYLRDQAA MYYAMAANNH
HPMGPHPGHH HGPGGMGPHP SLLPGGGSGQ IPPHHAAAMA NQQMPHMYGP HSAAAAAYNA
AAAAAAVMMN QGMVGGKGGH HFHGHPNHMP MRAIGPPPAG GPQQPPQSAP PMSGQQFNPR
GPPPPPVHLG QPPPNGAGGN QFSQYMPWQH AQQQQLRPPG SGGNFGSAPG QQSGVPTGQN
PNASLWGPPP QSNPWTVLPK QQQMQQPPNP NGANGRQMGS QQTGQNMRGQ SVPLQPPPLS
NQQQMRNNPN DLGYLANKAL YAGKQHPGQG AQVPPTQVHS NFGGFGGQGN APPPPPNQLQ
MMNQRNMSGI PNGPISPMDP FMPRPPAAGG AAPNQNAAFF GQNNLPGPMK DKDFQFLNNV
HVPLNIGGTM FQAPPPPPNA MVGSANKQQS PTALRFPQPH EYASLLPPNM NIYEMAFEPK
ESQYKWYLKL LETQGQDAAN KFTEVLRQVS TMMQQQQPQP QQPVNKPPQH LQQTYMNNMG
VQPQPPTQQQ QQQLMPRDAS FMQPLMSYQQ QQPPQQQQQP PQRNVNPFMG PLPPPSNPMP
SNVGLNDETP PLDINFNQQI DMVFNSILNG NEISQPILRD LFGVAGGSSS NNAGPSAMNG
GDMILNSNSS SSNNLLGGSK IFPNIGTGGS SANGVGGGGG PAVMNNHQGN MAKNTMGPNC
MLGGMPPQQQ GAANPPSGFM GNNSLLNNKE FMLGPNISGG GAGSTSSNSS SVPLYRRQGL
TMGNGHNLNS AGNSSASTSG HSLSSSTPDN ILNSSPNDIL AGLSTGSNTL IEALFQDQHQ
QQNNATLQKL LYNNFNASGL KGGVGGGDMD LFMGNNSFVN ALTDGVANSF HAPNYEQTSA
NSVNSSGGNN IIGGPNTTAT GAAGDGRNTT YAAVLSQGPQ AQEALQHHNY AHNAALTTGP
GGAAGLVGNG LAGLGLNVNN SANGDGGDKD PFAAIRELGQ GTNGFYNYFQ
//
