ID   A0A1I8M8A0_MUSDO        Unreviewed;       254 AA.
AC   A0A1I8M8A0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=ER membrane protein complex subunit 3 {ECO:0000256|ARBA:ARBA00020822, ECO:0000256|PIRNR:PIRNR010045};
GN   Name=101901677 {ECO:0000313|EnsemblMetazoa:MDOA002268-PA};
GN   Synonyms=LOC101901677 {ECO:0000313|RefSeq:XP_005177774.1};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA002268-PA};
RN   [1] {ECO:0000313|EnsemblMetazoa:MDOA002268-PA}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA002268-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005177774.1}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|RefSeq:XP_005177774.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the EMC3 family. {ECO:0000256|ARBA:ARBA00005376,
CC       ECO:0000256|PIRNR:PIRNR010045}.
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DR   RefSeq; XP_005177774.1; XM_005177717.3.
DR   STRING; 7370.A0A1I8M8A0; -.
DR   EnsemblMetazoa; MDOA002268-RA; MDOA002268-PA; MDOA002268.
DR   GeneID; 101901677; -.
DR   KEGG; mde:101901677; -.
DR   VEuPathDB; VectorBase:MDOA002268; -.
DR   eggNOG; KOG3188; Eukaryota.
DR   OrthoDB; 167603at2759; -.
DR   Proteomes; UP000095301; Unassembled WGS sequence.
DR   Proteomes; UP000694905; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008568; EMC3.
DR   InterPro; IPR002809; EMC3/TMCO1.
DR   PANTHER; PTHR13116:SF5; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3; 1.
DR   PANTHER; PTHR13116; UNCHARACTERIZED; 1.
DR   Pfam; PF01956; EMC3_TMCO1; 1.
DR   PIRSF; PIRSF010045; DUF850_TM_euk; 1.
DR   SMART; SM01415; DUF106; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        110..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   254 AA;  28789 MW;  4B665200C55D0B73 CRC64;
     MTELLIDPNI RVWVFLPIVL IAFFIGILRH YVSILIASQK KAEITQIQDS QAMIRARLLR
     ENGKYLTAQS FAMRKNFFNN EETGYFKTQK RAPVQQNSTA MITDMLKGNF VNMLPMVIIG
     GWINWMFSGF VTTKVPFPLT LRFKPMLQRG IELASLDAAW VSSASWYFLN VFGLRSIYTL
     VLGENNQADQ TQAQADAMTG AAMTMPQDPK VAFKAEWEAL EITEYQNALK TVDSELLQLT
     SSCDAVAQEN SIRH
//