ID A0A1I8M9K1_MUSDO Unreviewed; 299 AA.
AC A0A1I8M9K1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Fork head domain transcription factor slp2-like {ECO:0000313|RefSeq:XP_005191654.1};
GN Name=101888796 {ECO:0000313|EnsemblMetazoa:MDOA002631-PA};
GN Synonyms=LOC101888796 {ECO:0000313|RefSeq:XP_005191654.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA002631-PA};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA002631-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA002631-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005191654.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005191654.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR RefSeq; XP_005191654.1; XM_005191597.1.
DR STRING; 7370.A0A1I8M9K1; -.
DR EnsemblMetazoa; MDOA002631-RA; MDOA002631-PA; MDOA002631.
DR VEuPathDB; VectorBase:MDOA002631; -.
DR eggNOG; KOG2294; Eukaryota.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR047208; FOXG1.
DR InterPro; IPR018122; TF_fork_head_CS_1.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46617; FORKHEAD BOX PROTEIN G1; 1.
DR PANTHER; PTHR46617:SF3; FORKHEAD BOX PROTEIN G1; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00657; FORK_HEAD_1; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT DOMAIN 239..299
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 239..299
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 15..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 117..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 299 AA; 33895 MW; 8306AB665BB46498 CRC64;
MVKIDDPCSV VERVSDPHQH HHHQQQQHQT QLSGHHTATN NLPPSPQQHH PNLQQLHQQA
LIDTHNQLQQ FYKMARTPHL KSSFSINSIL PETVEDSNNS HHNKTSDNDH HLRQSFTNLC
DDVDGPDADS DLDVTSMSPP PPTDGSELSV NSNEEGSRHP HHNSGIPHHH HRHNNHPHHH
PDEESDLEDG LDPDVEAEDL DLDGDVDADG TEGDATETES KEGGEGNEKP VTDKKGNEKP
PYSYNALIMM AIRQSPEKRL TLNGIYEYIM TNFPYYRDNK QGWQNSIRHN LSLNKCFVK
//
