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Database: UniProt
Entry: A0A1I8MA20_MUSDO
LinkDB: A0A1I8MA20_MUSDO
Original site: A0A1I8MA20_MUSDO 
ID   A0A1I8MA20_MUSDO        Unreviewed;       455 AA.
AC   A0A1I8MA20;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   18-SEP-2019, entry version 20.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:MDOA002759-PA, ECO:0000313|VectorBase:MDOA002759-PD};
GN   Name=101901470 {ECO:0000313|VectorBase:MDOA002759-PA,
GN   ECO:0000313|VectorBase:MDOA002759-PD};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA002759-PD};
RN   [1] {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA002759-PA, ECO:0000313|VectorBase:MDOA002759-PD}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Aabys {ECO:0000313|Proteomes:UP000095301,
RC   ECO:0000313|VectorBase:MDOA002759-PA};
RX   PubMed=25315136; DOI=10.1186/s13059-014-0466-3;
RA   Scott J.G., Warren W.C., Beukeboom L.W., Bopp D., Clark A.G.,
RA   Giers S.D., Hediger M., Jones A.K., Kasai S., Leichter C.A., Li M.,
RA   Meisel R.P., Minx P., Murphy T.D., Nelson D.R., Reid W.R.,
RA   Rinkevich F.D., Robertson H.M., Sackton T.B., Sattelle D.B.,
RA   Thibaud-Nissen F., Tomlinson C., van de Zande L., Walden K.K.,
RA   Wilson R.K., Liu N.;
RT   "Genome of the house fly, Musca domestica L., a global vector of
RT   diseases with adaptations to a septic environment.";
RL   Genome Biol. 15:466-466(2014).
RN   [2] {ECO:0000313|VectorBase:MDOA002759-PA, ECO:0000313|VectorBase:MDOA002759-PD}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|VectorBase:MDOA002759-PA,
RC   ECO:0000313|VectorBase:MDOA002759-PD};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_005183507.1; XM_005183450.1.
DR   RefSeq; XP_005183509.2; XM_005183452.3.
DR   GeneID; 101901470; -.
DR   VectorBase; MDOA002759-RA; MDOA002759-PA; MDOA002759.
DR   VectorBase; MDOA002759-RD; MDOA002759-PD; MDOA002759.
DR   Proteomes; UP000095301; Whole Genome Shotgun Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095301};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095301};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    115    138       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    197    221       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       80    226       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      233    404       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   455 AA;  52248 MW;  F2A08B842AD97666 CRC64;
     MHKPLTDVHV LKETEEEYVA NEPEAPAPNH WRRQYMRGLS TTTSQGGVYY EALKGSSNSL
     VKGSRNFRPG SMRKVRRRAV FKNGDCNVLQ KNLTRRRLRF LQDMYTTLVD TQWRWTLLAF
     ALSFILSWLI FAVLWWLIMY THGDLEELHL PHNQEESGWQ PCVSAINGFT SCFLFSIETQ
     HTIGYGVRTT SEECPEAIFM MCFQSIYGVM SSAFMAGIVF AKMTRAKQRA QTLLFSKNAV
     ICQRDGSLSL MFRVGDMRKS HIIGAGVRAQ LIRTKTTKEG EVMTQHFTDL EIGADDCGSD
     IFFIWPMVIE HKIDENSPLY NMSATDILND KFEIVVILEG TVESTGQSTQ ARSSYINTEI
     LWGHRFDPVV VYNKDRQAYE IDYARFNETT QVDTPLCSAR DLNEIYKIQE GFTTPDICRQ
     FSPSLSGRHK SPPISPLYSA KQQNVVYRWQ FSNEI
//
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