ID A0A1I8MA53_MUSDO Unreviewed; 1587 AA.
AC A0A1I8MA53;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Protein sax-3 isoform X1 {ECO:0000313|RefSeq:XP_011291411.1};
GN Name=101898311 {ECO:0000313|EnsemblMetazoa:MDOA002787-PB};
GN Synonyms=LOC101898311 {ECO:0000313|RefSeq:XP_011291411.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA002787-PB};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA002787-PB}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA002787-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_011291411.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_011291411.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_011291411.1; XM_011293109.2.
DR STRING; 7370.A0A1I8MA53; -.
DR EnsemblMetazoa; MDOA002787-RB; MDOA002787-PB; MDOA002787.
DR GeneID; 101898311; -.
DR KEGG; mde:101898311; -.
DR VEuPathDB; VectorBase:MDOA002787; -.
DR eggNOG; KOG4222; Eukaryota.
DR OrthoDB; 5396194at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00063; FN3; 2.
DR CDD; cd05724; IgI_2_Robo; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45080; CONTACTIN 5; 1.
DR PANTHER; PTHR45080:SF8; WRAPPER_REGA-1_KLINGON HOMOLOG; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1031..1053
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 123..215
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 221..310
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 315..401
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 406..501
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 510..599
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 622..719
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 794..900
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 905..1004
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1130..1150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1174..1245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1467..1587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1467..1481
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1490..1587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1587 AA; 174221 MW; 273BE3A52C2C2308 CRC64;
MHLVGGFKFR NNLYVADNSK DDENDGIMTI TNRTRTYGLQ KQQQHQHLKK TNAVTASLSS
NSSVSVAAKR MATPTASART TTTANKHLGL MSMHLAVVLL VFLLADSGLN GLRLVTALKA
QNPRIIEHPK DMVVPKNDPF TFNCKAEGTP TPSIQWFKDG NELKTDSGSH RIVMPAGDLF
FLKVIHSRRE SDAGTYWCQA KNEFGVARSR NATLQVAFLR DEFRLEPQNT RVAQGEVALM
ECGPPRGSPE PQVSWRKNGQ TLNLSGNKRI RIVDGGNLAI QDVRQSDDGR YQCVVKNVVG
TRESSTAFLK VHTRPFLIRG PQNQTAVVGT SVIFQCRIGG DPLPDVLWRR TASGGNMPLR
RVTVLEDRSL KLDDITLEDM GEYTCEADNA VGSITATGTL IVHAPPKFSI RPKNQLVEVG
DEVIFECQAT GYPKPTVYWS IEGNSSLLFP GYKDTRLEVT VTPEGRSVLS IFRFAREDSG
KVVVCNALNA VGSVSSRTVV TVDTQFDLPP PVIEQGPVNQ TLPVKSIVTL PCRTLGSPIP
QVQWYLNGIP IDVMDHERRN MSDSGSLTIV DLMKNEDEGL YTCVASNRNG KSSWSGYLRL
DSPTNPNIKF FRAPELSAHP GPPGKPQVVD KTEDSISLSW TRSNKVGASS LVGYVVEMFA
KNETDGWTQV ASRVQNTTYT QVGLLPGINY FFLIRAENSH GLSLPSPMSE AIVVGTKYFN
SGLDLSEARA SLLSGDVIEL INASVVDSTS MKLSWQIING KYVEGFYIYA RQLLDTSAGS
TANTNPLVAA ARSSSSSSRS HSTSASSSAL ISASKPNIAR RDGTAYVVAS TTPSSVIQSA
AAYVGSTTYR MLTILNGGGA SSCTMTGLLQ YTLYEFFIVP FYKSVEGKPS NSRVARTLED
VPNEAPFGME AILLNSSAVF LKWKQPNLKA QHGVLLYYHI VVRGIDTAHN FSRILTNVTI
DAASPTLVLA NLTEGVMYTV SVAAGNNAGI GPYCSPATLR LDPITKRLDP FINQRYPINQ
DHVDDVLTQP WFIILLGAIL AIMMLSFGAM VFVKRKHMMM KQSALNTIRG THANDVLKMP
SLSRNGNGYW LDASTGGMVW RTQPSGDTLD MQKDQIDDYA PVCLTNNAAN GANNTNERGA
GSGSGQQRYV GEYSNIPTDY AEVTSFGKTG SEYSVGRKNA SSPAPYATSS IVQQQQQQQQ
QPRYQTRPGG PVFNMQQQQM TGSQQRPMHP LYQQQQQQQQ QPTTTNNIYQ QMSTTSEIYP
TQMASNRSAY SDQYYYPKEK IHITENKLSN CHTYDTANNQ QHQQPQQTTV AFSNMGTLRR
SANQQHSQRF KVINTQPQNY QLHLSDTTQH QKQQQIKMNS LNNNQNCIVG GNPDYNTQDM
ITKNLMDLDA GSFCYNGMAD SGCGGSPSPM AMLMSHDDEA GEEQALYHTA DGDNESDMER
LYVKVDDPPQ QQKQQQQQQQ LISLTPSHHP ATQQQQHQQH LHSASQERDA ANHGPYNNWR
SHNSSTRSNG SQYQRGAQMT VGDSQNAASQ QMHHLHPLHQ QQPSSDSEMI YAPSSSMASE
RSLLSNSGSS TCGGAASGSG SGQAHNV
//
