ID A0A1I8MHK3_MUSDO Unreviewed; 1949 AA.
AC A0A1I8MHK3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=AT-rich interactive domain-containing protein 2 isoform X1 {ECO:0000313|RefSeq:XP_011293515.1};
GN Name=101887407 {ECO:0000313|EnsemblMetazoa:MDOA004973-PB};
GN Synonyms=LOC101887407 {ECO:0000313|RefSeq:XP_011293515.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA004973-PB};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA004973-PB}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA004973-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_011293515.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_011293515.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_011293515.1; XM_011295213.2.
DR STRING; 7370.A0A1I8MHK3; -.
DR EnsemblMetazoa; MDOA004973-RB; MDOA004973-PB; MDOA004973.
DR GeneID; 101887407; -.
DR KEGG; mde:101887407; -.
DR VEuPathDB; VectorBase:MDOA004973; -.
DR OrthoDB; 5001776at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16100; ARID; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR22970; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR22970:SF14; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT DOMAIN 78..170
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 684..766
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 23..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 807..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 872..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1611..1718
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1845..1867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..918
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1641..1718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1949 AA; 212089 MW; E3266176E936554C CRC64;
MLITEISKAN TLSQSENTIV TGANTTNNAT ATTTSFTSSS SDAPKTGTPL RSRNRGDKQS
EDKPENASAS TGKGKNPPKP PEEFYRDLQL FHEKRGTIIR NIPRITGREV DLHRLYCEVT
ERGGFLKVNS RDQWDEVLKE LGWSEKIVNG SAGLKFIYRR YLEKYERVNY FGEDPEKIDA
MEAAEMAEFM GGRGGSKGSS RYPSSVYGGT GANPANNVAM TYNYKQHHVN MDRRRQFKLS
TDLHKSSPYE KLMLSLLSPL PNEQDFAINA CTLMANESKH TLKVNEYPKL IDALLAHTGV
YCDYTMRKLF QHVYNGVRQH SLYGFWYDLL HEQPQILDLY TDEQSLRDSG VIDDWDDGKQ
DVDEDGLWHD CKELYFLNLR RGLGTYDYVG QRVLQVVSIL RNLSFFPENL NVLVKNKTLI
RFLVMSSNIR WSNVHIQALE ITGNIAMELD LADPTIDDLS RCLMATICDG IDGSDRGVII
NCLEILYKLC QREANEDYVL KCLNAKFYNT ISLFLSLNDI MLLIFTLEAI YALTCLGPKS
CNSMMQVRGI VDQLISLISV EAQSYGTDGC ILMRVVETVP GNMLPMVAQN IANLQNAVVI
QKSNSSHQVM HKPQIMSNQQ PVMMADASIN PDVIPPFHHS PGVVVAPVEK QHFQQQQPSH
AQTTAIPPSQ MSPQSFTHED EQYALAWLGA TFERTPSSEC HIDQQELYRM YLSHCQKAGK
HSVVNHMQFP KLVRLLFTTA VGPAMVRKMD GTDLPGLHYV SIRLRAQPLP LQQKTNFIVS
GPNSPANKQI DNASQARKIK KKIKIETAST STTTSADAAT APPGVENVKT TVPTTVSVAS
TTGSEVGETA TTSEATNTQS VDIKCDEKMN IEESEPATKS EEMSAVAATT NTSQSQSVEP
SVVFSEVQQT PQTQSQSLAS QTSLIKSLLA NKVNQRQQKQ KDSVATNNCA ATSNVSTTTT
NVITTNSSPL PQPTAPAITA QPIKVPSTAI TALVNNPLMQ NTPVKVGQTT IKPLNPQLAM
EKKHISESTP PPLAPLSGAN VAKDASGRPI LLANQMLVDI LDKKMVDPPV PGGLIQKRKV
EEQMQPNKRL AGDALTSNAS ISKEETQVTP SKNAANLYAE MAASILEDED LEELAATRTT
TTNVNKEPTP SLTQPSLLVQ QTTSSAGTLP RQLVFQTNQP PQLKINQGAG PVQGPMHQLP
NAMATIKTDQ GLQTVPVIVH QKPLVDNSQP QQIIQQVIQP TPNQAPTQYV LATNQQGQTY
LVAQQAPQPP PQPQPTQTVL VTQTPQQQST GAKTIIILQQ NTLPGQGSQQ QIITTTTQGQ
QQKMIMTTPQ GQQVLVTQRP QTPQQIFINP QTGTATHIQP RQIIQTATPP TVAPTISTQQ
PQQGSNQIQA GQMSPSLLNQ LNQIPATIKL HQPVPQQATT MVSQPPGTMG RMNTTINKGV
SIVQQATTPP TPVAIPQLQQ HQSIIQQHII SGPSEKRHVI LGAGRAIEIK ETVITQTQPP
PQQCQLNPQT IITTQHPQMV NSQQQQQTQQ TMESAAPPSL IASQTPSLIA SNQNAIKKST
ILPATTPTPT LIKPSLPTVK LPPNIGSGGP PPLAAVTSSI ATTASTPVTV VNPTTTPIPT
TLEKDNNKKD DIGTKPALPL LPPSITSTST VPTTGSLITP SSSTSTPVAG QTTNTTMSSN
STNNTSATVS STATSSSSGT TMPTVPATGP TPQSTSLTQP TAAVPQTVVP QLTAADAQWL
FICDWRNCPR KKFKSLSDLQ HHVCTKHAPD HLDPSAEIFC QWGIGPGLCD GIPRKRFSLM
THLIDRHLTV ESLGAAVQRR IATGAHNIAP SKPPVTIVRN IELSQRTNTS SPSSSSSSSQ
AAATGSSALQ AIKRHTADFM NSKELMDENE GPVTKSIRLT AALILRNLVI YTSTAKRSIR
RYEPHLANIA LSNVESSGTI SHILYELNN
//
