ID   A0A1I8MI98_MUSDO        Unreviewed;       772 AA.
AC   A0A1I8MI98;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Regulating synaptic membrane exocytosis protein 1-like {ECO:0000313|RefSeq:XP_005188586.1};
GN   Name=101889830 {ECO:0000313|EnsemblMetazoa:MDOA005165-PA};
GN   Synonyms=LOC101889830 {ECO:0000313|RefSeq:XP_005188586.1};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA005165-PA};
RN   [1] {ECO:0000313|EnsemblMetazoa:MDOA005165-PA}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA005165-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_005188586.1}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|RefSeq:XP_005188586.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_005188586.1; XM_005188529.3.
DR   STRING; 7370.A0A1I8MI98; -.
DR   EnsemblMetazoa; MDOA005165-RA; MDOA005165-PA; MDOA005165.
DR   VEuPathDB; VectorBase:MDOA005165; -.
DR   eggNOG; KOG2060; Eukaryota.
DR   eggNOG; KOG3528; Eukaryota.
DR   OrthoDB; 4502832at2759; -.
DR   Proteomes; UP000095301; Unassembled WGS sequence.
DR   Proteomes; UP000694905; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006887; P:exocytosis; IEA:InterPro.
DR   CDD; cd00992; PDZ_signaling; 1.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 2.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR039032; Rim-like.
DR   PANTHER; PTHR12157:SF24; FIFE, ISOFORM D; 1.
DR   PANTHER; PTHR12157; REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN; 1.
DR   Pfam; PF00168; C2; 2.
DR   Pfam; PF00595; PDZ; 1.
DR   SMART; SM00239; C2; 2.
DR   SMART; SM00228; PDZ; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR   SUPFAM; SSF50156; PDZ domain-like; 1.
DR   PROSITE; PS50004; C2; 2.
DR   PROSITE; PS50106; PDZ; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT   DOMAIN          5..89
FT                   /note="PDZ"
FT                   /evidence="ECO:0000259|PROSITE:PS50106"
FT   DOMAIN          102..232
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          637..755
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          102..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          242..262
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          325..367
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          382..456
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          490..606
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        398..442
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        533..551
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..606
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   772 AA;  84464 MW;  F4562FCCF9E6E377 CRC64;
     MPPLSAVIVN EPRGFGMRVV GGKTGADGRL FAYIVWTVPG GPAEKNGLQQ GDKILEWNGM
     SLIDRSFEEV CSIMDRTGDI VELLVEHATD FRMCDLFDEN LPPGNSGGSE RGPRRSGDGP
     VGLGLIADPE TTTDKSPASP TRRKLPKTPN CVENAIIGDG SVQQTEVSPP TQNPIWNATL
     SFAHVKAEHL MDRYIDIQLW DLVPHTESIF LGECNIELQQ VFLDDRAIWC RLEDPKGLRG
     ISMSKSPSVS PRGSIAAGGP GGDVSRLLRR DYNMQRSISD DVDSIGECTS LLHPDHAWIA
     GSRRGSSQSE TLEVEVYQLG KDFSRSLPGS RRSSFQDADK NREDDMAPPP ATYLVGRRRS
     SVARRDPEEI LKSLKAVGRA MSLGTEQTVK RMGSRRTSRV GLPSNPSSRK SSVFDLSQQQ
     QQQQLPMGLG NAATSPPSDD ESKTNFPPRW KGSGGNMLPA TPKQALSMLK QASSATNVSE
     RQYYLGSQLT DSPQNMRKGS VYNLRPDDSP QRKSSIYAMN AGETLAPRQQ RKGSMYVASS
     SSGTGTAPNA GSSLMVHEPL RKNSIMAPST PDSPSMSRKS SVVPSNSSAK SYKSLSDSSS
     NLSTTVSSSL SATSTSYGLQ LGPGQIHPKG YRLTMERHGE LRMGFSKVKG YVEVELICAR
     KIVPVDCETP PDTYVKCYIK DGDRLRHKKK TRVVRHSAEP IYKQTIKYQC SDVFGRNIVI
     MVWQRCVGFE HNQGLGGTEV NLDKLNMDEH VNGWYPLFPM HSFGGSDSDN SP
//