ID   A0A1I8MLG1_MUSDO        Unreviewed;       833 AA.
AC   A0A1I8MLG1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Inositol-pentakisphosphate 2-kinase {ECO:0000256|ARBA:ARBA00014846};
DE            EC=2.7.1.158 {ECO:0000256|ARBA:ARBA00012023};
DE   AltName: Full=Inositol-1,3,4,5,6-pentakisphosphate 2-kinase {ECO:0000256|ARBA:ARBA00030342};
DE   AltName: Full=Ins(1,3,4,5,6)P5 2-kinase {ECO:0000256|ARBA:ARBA00029574};
GN   Name=101895533 {ECO:0000313|EnsemblMetazoa:MDOA006184-PB};
GN   Synonyms=LOC101895533 {ECO:0000313|RefSeq:XP_011290681.1,
GN   ECO:0000313|RefSeq:XP_019890772.1};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA006184-PB};
RN   [1] {ECO:0000313|EnsemblMetazoa:MDOA006184-PB}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA006184-PB};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_011290681.1, ECO:0000313|RefSeq:XP_019890772.1}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|RefSeq:XP_011290681.1,
RC   ECO:0000313|RefSeq:XP_019890772.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the IPK1 type 2 family.
CC       {ECO:0000256|ARBA:ARBA00007229}.
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DR   RefSeq; XP_011290681.1; XM_011292379.2.
DR   RefSeq; XP_019890772.1; XM_020035213.1.
DR   STRING; 7370.A0A1I8MLG1; -.
DR   EnsemblMetazoa; MDOA006184-RB; MDOA006184-PB; MDOA006184.
DR   GeneID; 101895533; -.
DR   KEGG; mde:101895533; -.
DR   VEuPathDB; VectorBase:MDOA006184; -.
DR   eggNOG; KOG4749; Eukaryota.
DR   OrthoDB; 8233at2759; -.
DR   Proteomes; UP000095301; Unassembled WGS sequence.
DR   Proteomes; UP000694905; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0035299; F:inositol pentakisphosphate 2-kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.200.110; Inositol-pentakisphosphate 2-kinase, N-lobe; 2.
DR   InterPro; IPR009286; Ins_P5_2-kin.
DR   InterPro; IPR043001; IP5_2-K_N_lobe.
DR   PANTHER; PTHR14456; INOSITOL POLYPHOSPHATE KINASE 1; 1.
DR   PANTHER; PTHR14456:SF2; INOSITOL-PENTAKISPHOSPHATE 2-KINASE; 1.
DR   Pfam; PF06090; Ins_P5_2-kin; 2.
PE   3: Inferred from homology;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   REGION          27..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          136..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          368..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          568..590
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..49
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..167
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        369..388
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   833 AA;  92771 MW;  F35606C88B5075A4 CRC64;
     MASETSSCAS SCLQSNEAPK ELLELLSVLD KQQKQQQQQQ LPQHGHNSNM NMEGKEEAEN
     MPQQKQKLDP SIQLPEKTRM DLSQIELIYR AEGNANLVLA LPQFKKVLRL PKIQQKQQNE
     QQADQLSLQE LQQMNELKQQ PQHQDTQYSQ KCPGPNTQQQ HRQQEQHYYP KQQQEHSKLK
     QQEPTNMTLT ATGQQLLQQP QSANAVGILT MDHYVAYIGI IRCLLGNEFV FEADIVAVPN
     PNDRDWINEH IRPHRPVNRL DKEFGGHYGL LLPDATRLPA EFDILFSNLK QTKSKQQCPQ
     RCCPAVAVQD AACGAGASNN SIFLEDTFAI EIKPKQGWLL PNDVNNLFDI KPATAAAGVT
     AMQQPDSLAD VGDATSSSSS SSTSTGTLKT SADKECFTAT QNKSSITKTT TSPLQKSLSA
     ASKAATVGGA GAASHDKVDI RCRYCSMQFL KLQQKKILQR SNYCPIDLFS GVPARMWNAL
     HALFTCPQNN LRIFKNGIVV FDDQLSRLSK IEDLFSSQQL QIIKQLMVIC LLRDYTPLQQ
     APTAFHANLP TADDDDLAYD ANASRQSDAQ MTAMELSHDD DGKPQTSETT PCKKLKTIKA
     ETGPESDVAK VNTTFIKANT TTRISTKSNS EMAAGITMTT TTTITPTTTT QFNDAKKSSL
     AYKASDSRPH CPTSVGADVS VKPKEKNIPE MLSLPKNCVL EKILNLQLLA KKHFPHMFKE
     NYQKKKGKSY DILSTLLQKY KCGPTKLEIS QLSAEEQYLL AATALDCSIM ITFRQISNQV
     MANCSLCTNP HMICIEGQHF ITKITLLDLD PKPDTHFAKY VKQTHEIMQS IHS
//