ID A0A1I8MMK6_MUSDO Unreviewed; 913 AA.
AC A0A1I8MMK6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=WW domain-containing adapter protein with coiled-coil isoform X2 {ECO:0000313|RefSeq:XP_011296004.1};
GN Name=101897836 {ECO:0000313|EnsemblMetazoa:MDOA006528-PB};
GN Synonyms=LOC101897836 {ECO:0000313|RefSeq:XP_011296004.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA006528-PB};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA006528-PB}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA006528-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_011296004.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_011296004.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_011296004.1; XM_011297702.2.
DR STRING; 7370.A0A1I8MMK6; -.
DR EnsemblMetazoa; MDOA006528-RA; MDOA006528-PA; MDOA006528.
DR EnsemblMetazoa; MDOA006528-RB; MDOA006528-PB; MDOA006528.
DR VEuPathDB; VectorBase:MDOA006528; -.
DR eggNOG; KOG0152; Eukaryota.
DR OrthoDB; 5406893at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR InterPro; IPR038867; WAC.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR15911; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR PANTHER; PTHR15911:SF6; WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT DOMAIN 247..274
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT REGION 1..250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 284..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..791
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..45
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..143
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..224
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 284..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..344
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..424
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..791
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 98158 MW; 4266606BF06FBD64 CRC64;
MVMHARKPQR MNDGYFEKHQ SHSYQSSKYS SKRDYERDRS SNYRDRDLSP AGGGPLNNGN
SSSYRSQSPE IDSPSSRGHG GSHDIRDRGD HRRSDPFSYM QKMRDRDRDI YKKDKYSDKR
DRRGDRDSES HRTNHDRLDR RGGGSVSGAK LCSSGDKRSG SDDRDRDRGD RDRDRDRDRD
LRDSKRDRDS LRDRERDRDR DRDRDRDRDR SARGGDDRDR DRGGGGGGGG SGDRNDRGER
IARCGDWSEH VSSSGKMYYY NCKTEVSQWE KPKEWIERER NLARDQHREK DYRDKERDRD
REERFSRSSY KHSSSRGNSR LRWNYDNDSG PPNHRRRIDG RMADNPDMDI SPGDSTPTSE
ASYSLTGTPT IYVGGNQHND EALPSTTVVL PNALPRLASH PNASSSNMTS SSVNASSLAS
SSGGAAASMH YPATCPSTAT GAGSVGGGGG GGSGSSGIVV GGATMLPATG LATTNVAGTI
PSAANTLSSS GNSNNSNHRK LDAVTALHQS HMGAVGSPNT PVPSSSSQVD HHLNSNAPGP
PKLGSKDPAL LMRQQQIHHH INNPDGHLIS PSPGDNNHAS AQQVMNLREN ALNSPLYNLT
HPHGMSPMGY SKSPITSSTS AVSGSAVPTA VGPGSLHTTA SVAHANNVNS GGMPITSLAA
ATSSYSCTNP YGLKTVDGNV VLNSNNVVGM NPLSVATNVA VGVAGGAVNV GNNNTLCSTS
MLSANPNMAG AIVGGGGSGG VGVMCAGVSG VGSSNVVNMN VIPGEGPPTP TQELDLSGSS
SIDPQQRKLD GTTSASLSTL QSCVSNSIQA GRSQGPEIST KLSKYFRADL ITHVTNWAAD
QLEKQAQKCS EEAHLYGDLQ CTKVSAELKC ARSLVRITEI TATLQEQKIM YLRQQIRRIE
ESKSQNSFMS DDL
//
