ID A0A1I8MQB1_MUSDO Unreviewed; 143 AA.
AC A0A1I8MQB1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Probable prefoldin subunit 2 {ECO:0000313|RefSeq:XP_005188774.1};
GN Name=101892871 {ECO:0000313|EnsemblMetazoa:MDOA007343-PA};
GN Synonyms=LOC101892871 {ECO:0000313|RefSeq:XP_005188774.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA007343-PA};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA007343-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA007343-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005188774.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005188774.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Binds specifically to cytosolic chaperonin (c-CPN) and
CC transfers target proteins to it. Binds to nascent polypeptide chain and
CC promotes folding in an environment in which there are many competing
CC pathways for nonnative proteins. {ECO:0000256|ARBA:ARBA00024667}.
CC -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC subunits. {ECO:0000256|ARBA:ARBA00011695}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000256|ARBA:ARBA00008045}.
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DR RefSeq; XP_005188774.1; XM_005188717.3.
DR STRING; 7370.A0A1I8MQB1; -.
DR EnsemblMetazoa; MDOA007343-RA; MDOA007343-PA; MDOA007343.
DR GeneID; 101892871; -.
DR KEGG; mde:101892871; -.
DR VEuPathDB; VectorBase:MDOA007343; -.
DR eggNOG; KOG4098; Eukaryota.
DR OrthoDB; 178677at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR Gene3D; 1.10.287.370; -; 1.
DR InterPro; IPR027235; PFD2.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR009053; Prefoldin.
DR PANTHER; PTHR13303; PREFOLDIN SUBUNIT 2; 1.
DR PANTHER; PTHR13303:SF0; PREFOLDIN SUBUNIT 2; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905}.
FT REGION 119..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 12..39
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 143 AA; 16554 MW; 3ADA401DEE9B0DCD CRC64;
MSGEQVKDSK MNEKIIAEFQ QLRNEQRNLV NNLNTLEMDL KEHKTVIDTL KTVDPNRKCF
RLIGGVLCER TVKEVLPQLV ENKDFIEKTI TLVTDDLTKK GQQINKFKEE HNIRIRGEQM
AGEAQKSQSE ENKSENRNVL VSN
//
