ID A0A1I8MY80_MUSDO Unreviewed; 312 AA.
AC A0A1I8MY80;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN Name=101899844 {ECO:0000313|EnsemblMetazoa:MDOA009644-PA};
GN Synonyms=LOC101899844 {ECO:0000313|RefSeq:XP_005177840.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA009644-PA};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA009644-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA009644-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005177840.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005177840.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361218}.
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DR RefSeq; XP_005177840.1; XM_005177783.3.
DR STRING; 7370.A0A1I8MY80; -.
DR EnsemblMetazoa; MDOA009644-RA; MDOA009644-PA; MDOA009644.
DR GeneID; 101899844; -.
DR KEGG; mde:101899844; -.
DR VEuPathDB; VectorBase:MDOA009644; -.
DR eggNOG; KOG3882; Eukaryota.
DR OrthoDB; 2879418at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd03159; TM4SF9_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF431; TETRASPANIN 26A, ISOFORM B; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 2.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 55..79
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 91..116
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 237..256
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
SQ SEQUENCE 312 AA; 35825 MW; DA484B26FA689A83 CRC64;
MPVRKYRHET REVSCCTKYL LFVCNTLLWM TGLIILAAGV WAWNEKDAFS NQFKLTLLVL
DPAFVLICTG SVAFLIGFTG SVGALRENTC LLGTFIVLMC VLLVVEVCFG VLYLVLKDKG
WIKDQATEGL RAFIIHYRED PDQQNLIDWI QEDWLQCCGI EGPKDWDSNN YFNCSSSAIG
SREACGVPFS CCRRQPHELI KNKQCGYDVR KEGYPVDRHI YERGCLRAGE EFLEMHIVSI
WIYIMVTVFC QSFEIAKIIY DKGCVQAGEE WMERNLILIS TSAIIAIFFQ ILFVIFTQNL
RADINSQKSK WH
//
