GenomeNet

Database: UniProt
Entry: A0A1I8MZR3_MUSDO
LinkDB: A0A1I8MZR3_MUSDO
Original site: A0A1I8MZR3_MUSDO 
ID   A0A1I8MZR3_MUSDO        Unreviewed;       521 AA.
AC   A0A1I8MZR3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   18-SEP-2019, entry version 22.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:MDOA010060-PE};
GN   Name=101900907 {ECO:0000313|VectorBase:MDOA010060-PE};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA010060-PE};
RN   [1] {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA010060-PE}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Aabys {ECO:0000313|Proteomes:UP000095301,
RC   ECO:0000313|VectorBase:MDOA010060-PE};
RX   PubMed=25315136; DOI=10.1186/s13059-014-0466-3;
RA   Scott J.G., Warren W.C., Beukeboom L.W., Bopp D., Clark A.G.,
RA   Giers S.D., Hediger M., Jones A.K., Kasai S., Leichter C.A., Li M.,
RA   Meisel R.P., Minx P., Murphy T.D., Nelson D.R., Reid W.R.,
RA   Rinkevich F.D., Robertson H.M., Sackton T.B., Sattelle D.B.,
RA   Thibaud-Nissen F., Tomlinson C., van de Zande L., Walden K.K.,
RA   Wilson R.K., Liu N.;
RT   "Genome of the house fly, Musca domestica L., a global vector of
RT   diseases with adaptations to a septic environment.";
RL   Genome Biol. 15:466-466(2014).
RN   [2] {ECO:0000313|VectorBase:MDOA010060-PE}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|VectorBase:MDOA010060-PE};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   VectorBase; MDOA010060-RE; MDOA010060-PE; MDOA010060.
DR   Proteomes; UP000095301; Whole Genome Shotgun Assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 2.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095301};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095301};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     83    106       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    169    193       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       49    198       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      205    378       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      410    430       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      470    521       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    470    512       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   521 AA;  59371 MW;  9E66536F7E80CD2B CRC64;
     MPEIKRSLSR LSMLVFRATH SSEQSWRDEL LRYRQTRFSS RRIRKRVIFK HGDCNVVQGN
     VAKRRRRYLQ DIFTTLVDAQ WRWTLLVFAC SFLISWAFFG LIWWTIAYAH GDLEWIDNRD
     NRPELIQNMT HTMCVTEVRS FISAFLYSIE TQHTIGYGNR FVTEECPEAI FTICLQCITG
     VFIQAFMVGI VFAKLSRPKK RAQTLLFSRN AVICHRDGVP CLMFRVGDMR KSHIIEAHVR
     AQLIRKKVTK EGEVLPFYQQ ELKVGADGGE DRLMFIWPTT IVHKIDRHSP LYMLSASDML
     KERFEVVCML EGVIESTGMT TQARSSYLPS EILWGHRFVN VVSFRKETGE YEVDYTLFNN
     TYDVDTPLCS SKELDDLKEE YSKNHKAGLD RALSAGLLKH ISSVASVDHM DPASDESLDS
     GRLHTRSNSI PNGALATELE PLNNNTPSFT VGGSSILPSI TTNFQSINEK INSTNGSSTH
     NNNNNNSGSN INHSSSNTSL KAKSSRRLSI KQDQLPVDSL C
//
DBGET integrated database retrieval system