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Database: UniProt
Entry: A0A1I8N5Q4_MUSDO
LinkDB: A0A1I8N5Q4_MUSDO
Original site: A0A1I8N5Q4_MUSDO 
ID   A0A1I8N5Q4_MUSDO        Unreviewed;      2886 AA.
AC   A0A1I8N5Q4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   07-NOV-2018, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:MDOA011823-PB};
OS   Musca domestica (House fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Musca.
OX   NCBI_TaxID=7370 {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA011823-PB};
RN   [1] {ECO:0000313|Proteomes:UP000095301, ECO:0000313|VectorBase:MDOA011823-PB}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Aabys {ECO:0000313|Proteomes:UP000095301,
RC   ECO:0000313|VectorBase:MDOA011823-PB};
RX   PubMed=25315136; DOI=10.1186/s13059-014-0466-3;
RA   Scott J.G., Warren W.C., Beukeboom L.W., Bopp D., Clark A.G.,
RA   Giers S.D., Hediger M., Jones A.K., Kasai S., Leichter C.A., Li M.,
RA   Meisel R.P., Minx P., Murphy T.D., Nelson D.R., Reid W.R.,
RA   Rinkevich F.D., Robertson H.M., Sackton T.B., Sattelle D.B.,
RA   Thibaud-Nissen F., Tomlinson C., van de Zande L., Walden K.K.,
RA   Wilson R.K., Liu N.;
RT   "Genome of the house fly, Musca domestica L., a global vector of
RT   diseases with adaptations to a septic environment.";
RL   Genome Biol. 15:466-466(2014).
RN   [2] {ECO:0000313|VectorBase:MDOA011823-PB}
RP   IDENTIFICATION.
RC   STRAIN=Aabys {ECO:0000313|VectorBase:MDOA011823-PB};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   VectorBase; MDOA011823-RB; MDOA011823-PB; MDOA011823.
DR   Proteomes; UP000095301; Whole Genome Shotgun Assembly.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095301};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095301};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2413   2443       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2455   2475       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2487   2511       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2539   2567       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2588   2610       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   2707   2730       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      115    169       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      176    228       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      236    292       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      299    354       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      410    466       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   COILED     2073   2093       {ECO:0000256|SAM:Coils}.
FT   COILED     2845   2865       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   2886 AA;  325455 MW;  76A9A1C677BB3322 CRC64;
     MGDNIIGSAS FLHLGDIVSL FAEGSVCGFL STLGLVDDRT VVCPEAGDLN YPPKKFRDCL
     IKVCPMNRYS AQKQFWKAAK QSASSNTDTN LLKRLHXXAE IEKKQNETEN KKLLGTAIQY
     GSVVQLLHLK SNKYLTVNKR LPSLLEKNAM RVYLDANGNE GSWFYIMPFY KLRSIGDNVV
     VGDKVILNPV NADQQNLHVA ANYELPDNPG CKEVNVLNSS TSWKITLFME HKENQDHILK
     GGDVVRLFHA EQEKFLTMDE YKKQQHVFLR TTGRTSATAA TSSKALWEIE VVQHDSCRGG
     AGHWNSLYRF KHLATGYYLA AELDSENGGS LGSGISASSV GQLQQQQQIH QTPTQLLNIS
     AENAKDSGIS CNSTMIDKGK LEHYRLVSVP FSTDIATVFE LDPTTMARAD SLVPQSSYVR
     LRHLCSNTWV HATSIPIDID DDKPVMSKVC CSPVKEDKEA FALIPVSPVE VRDLDFANDA
     CKVLVVVTAK LDNGTISINE RKSLISLLQD IVYFIAGMEN EQNKTKALEL TIKNPIRDRQ
     KLLREQYILK QLFKILQGPF QEHPGGDGPF LRLDELSDPK NSPYKNIFRL CYRILRLSQQ
     DYRKNQEYIA KHFGLMQKQI GYDILAEDTI TALLHNNRKL LEKHITAAEI ETFVGLVRKN
     MHNWDSRFLD YLSDLCVSNR KAIAVTQELI CKSVLSTKNS DILIDTEVKI VKAPKFGFPK
     QSDINKPLSP LTEVVDDDDK LDLISTKTSS TWDLRSLDGD AEGDNVKYEI HLKWKGLKES
     RSMADLANCV AQGKEQEIAI LNYYRHQLNL FSNMCLNRQY LALNNLSPHL DIDLILKCMS
     DETMPYELRA SFCRLMLHLH VDRDPQEPVT PVKYARLWSE IPSKMSILDY DGKNQQPDYN
     KEAVRAKFNT TIAFVENYLC NVAAKVWLFT DQEQNKLTFE VVKLARDLIY FGFYSFSDLL
     RLTKTLLCIL DCVSDSSIDS STAAGPNAGR FEAAVTDSEG GVLRSIGDMN TVMTSLALGS
     VGQVMATPAI SSLQQRKSVS QLMKEFPLVM DTKLKIIEIL QFILDVRLDY RISCLLSIFK
     REFDESDAHQ YANQSEAATA TVTSAPYVQT STTTITTTSD SGISSSSAST AAGVSGGGGG
     GGDNTSTSNT TSSTSTSNTN TTSGTQDAQS SAAAAAAFQQ RQKNIDLESI GIQAEGIFDC
     DSGDAANLDL DGQGGRTFLR VLLHLIMHDY PPLVSGALHL LFRHFSQRQE VLHAFRQVQL
     LVSDNDVESY KQIKHDLDIL RQSVEKSELW VYKSKTSEEL STTVGESSID NSNLTNEYRA
     SLSTEQLAEY KKVKEILIRM NQFCVTQGPY VKPRKHEQRL LRNVGVHTVV LDLLQNPYDE
     KDDVLMKELM FLAHEFLQNF CLGNQQNQVL LHNHLDLFLN PGILEAKTVC AIFKDNLTLC
     NEVTDKVVQH FVHCIEIHGR HVVYLQFLQT IVKAENQFIR KCQDMVMQEL INAGEEVLVF
     YNDKSSFNQL VHMMQTQKTP LSDDSPLKYH VELVKLLACC TMGKNLYTEI KCNNLLSLDD
     IVAVICHPAC IPEVKEAYVD FLNHCYIDTE VEMKEIYSSG HMWNLFEKSF MVDINLLINT
     GINADKTLIN YVLNGICTIL ASFFSSPFSD QSTIVQSRQM IFVQLLQVCY RLSQCKWLSL
     ADRFNVENCI RTLAESAKTR SIAIPLDLEQ QVVTMSSKTA LLTRQTTKWL LASKQPKYET
     QHSANLMRLD RSIIEGLQDI VSLLEDQLKP VVEAELSLLV DILYRSELLF PQGTEARKRC
     ESGGFIRKLI KHTEKLLEEK EEKLCVKVLK TLREMMAIDV NYGEKGDALR STLLKRYFDI
     KPSNTSRTPV EPKTDILSLT QDPQKQHLNL VTHGPGAKYL QRAEKTLHEV QNHLDREGAS
     DLVIELVIKS VHSPSIFVEA IELGIALLEG GNPIIQKGMY TKFLSGDLNQ AFFKVFFDKM
     KDSQQEIKST VTVNTSDIAA KAHESKQDVN LELDKISRKH GVKTNGVVIT DELRKELHNA
     GLATARAFSN ARNLHAGEDS NSLNLNSPFD DILAEKLEKH KDNKEDRNKL SNKVLVMQPI
     LRFMQLLCEN HNPDLQNLLR NQNNKTNYNL VSETLMFLDC ICGSTTGGLG LLGLYINENN
     VALINQTLET LTEYCQGPCH ENQNCIATHE SNGLDIITAL ILNNINPLGE NRMDLVLELK
     NNASKLLLAI MESRGDGENA ERILYNMNPK QLVDVACKAY HQEEMIDDHD GDEDGVAAEH
     DDDDDVSVSP REVGHNIYIL CHQLAQHNKE LASLLKVSED PQSPNYDAKM SQALMYYATH
     TAQIEIVRHD RTLEQIVFPI PEICEYLTTD TKMKIFQTAE RDDQGSKVAD FFDKAEEMFN
     EMKWQKKLRG QPFLFWVSSY MSLWSNILFN CVVVINIIVA FFYPFDNTVP ELSSHISLLF
     WAIMIFSLVI VVTLPRESGI RTLIGSIILR SIFLLGPEST LCLLGVVTVT LKSVHIISIM
     GNKGTLEKHF LKIITDFQLL YHCIYIFFCF CGLIFHPFFY SLLLFDVVYR EETLVNVIRS
     VTRNGRSIVL TAVLALILVY LFSIIGYMFF RDDFLLEVDV DHVENAVEAA TLSVNPDSTC
     STPDSLENPK LITTGDGEVK ERSCDSLVMC IVTTLNQGLR NGGGIGDILR APSSKEGLFA
     ARVIYDLLFF FIVIIIVLNL IFGVIIDTFA DLRSEKQQKE LILKNTCFIC GLNRSAFDNK
     TVSFEEHIKS EHNMWHYLYF IVLVKVKDPT EFTGPESYVY AMVKAGILDW FPRLRAMSLA
     AVDADGEQIE LRSMQAQLLE TQMLITNLSQ QLHELKDHMT EQRKQKQRLG LLNTTASSFM
     TGYQFQ
//
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