ID A0A1I8NA68_MUSDO Unreviewed; 1243 AA.
AC A0A1I8NA68;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=RNA recognition protein {ECO:0008006|Google:ProtNLM};
GN Name=101889074 {ECO:0000313|EnsemblMetazoa:MDOA013152-PB};
GN Synonyms=LOC101889074 {ECO:0000313|RefSeq:XP_005185632.1,
GN ECO:0000313|RefSeq:XP_011293374.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA013152-PB};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA013152-PB}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA013152-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005185632.1, ECO:0000313|RefSeq:XP_011293374.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005185632.1,
RC ECO:0000313|RefSeq:XP_011293374.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_005185632.1; XM_005185575.3.
DR RefSeq; XP_011293374.1; XM_011295072.2.
DR STRING; 7370.A0A1I8NA68; -.
DR EnsemblMetazoa; MDOA013152-RA; MDOA013152-PA; MDOA013152.
DR EnsemblMetazoa; MDOA013152-RB; MDOA013152-PB; MDOA013152.
DR GeneID; 101889074; -.
DR KEGG; mde:101889074; -.
DR VEuPathDB; VectorBase:MDOA013152; -.
DR eggNOG; KOG2068; Eukaryota.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00723};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 13..56
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 108..192
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 189..216
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT ZN_FING 189..216
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 250..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 983..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1119..1144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1158..1184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1197..1223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 342..366
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..450
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1002..1016
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1137
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1167..1181
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1243 AA; 136955 MW; 1644F67DCBDED99B CRC64;
MNNLNNTDDI VECPLCMEPL EVDDLNFFPC TCGYQICRFC WHRIRTDENQ LCPACRKEYP
ENPADFKPLS QEEMVAFKFQ KRQRDQKRKQ EITENRKHLA NVRVVQKNLV FVVGLPPRLA
DAEILKKHEY FGKYGKIHKV VINPSTTYAG VQGPSASAYV TYVHNPDALR AIQSVNNITI
DGRLIKTSLG TTKYCSHFMK NQQCPKSDCM YLHELGDPEA SFTKEEMHQG KHQDYEKRLH
EALIATAGSS TTGGGLVSTT TPSSSSASSG GILSGNGKST DSSYKSSGLA TSKSANAINN
GHDSSSGGTT APAVNGGQQS SSEAWPSLFV WPVIKKDEAN PANGGPKSKK ERQKQEKTKP
EKNGKAKNKN SNSTSNNNNN HNNNSNSNTN PASKDPVEAT HTNNSKSATA AVADSDKTRT
TDKDRDRKQQ QQQQQQNSHS TSNNSQNQRK EELPARTETV ETSKTNSKTK TASTDSNNSK
SQATNSERDR SKNECKQESA TPPATTTENT MYVSNSSNSS LSSSSSSSSS TSNSSSSSTA
SNGNLSSETT TTQQIQKSNS VEEPLASATA TTTTAASPPA TTITTSDSLE KSATCPFTES
IERTAASIPD NFSVFGNKNK SPLYNGINSS IDEGDKIKNS IESTQSATLL STTISDVPKL
SLFDDRSFFS LNPDKISQMP PLQQQQQHTA SLLNNKLLED PLLTGRTMPN LPDLINGIDG
YQSNLNCSND WEDAFKSVIL KTNKQMEEKM QQQQQLQQHL NSHLHLKTQE DLRKLQELQK
RNILLNSMRV SQLGGPLGPL GSDLGRHSHF MAQQNPLLQH QPNLSSENLL QNSAQLPFET
NMSKFFDFHK HQQQQKLQHY GGGIGGPAAG GLGSLSDNFH MMSLLENKPL NSQLLDPNSL
LNSHLQQQQQ KQKQQLYGKI DPMMHHQQQL QQQQALNKNL SNMHGNQNHL KSQYLQNSNA
DDDLGFDPFI ETQKALAELI ENEEEQQQLQ QHNHVPTSHS NPIGPPKQPQ TQPTPPHQQD
PMLEYMQRLR MPPPGFSHHN SNLGGYGGMD PRMHSNQNSK MLPFMNLPGT NNGGAGNPPH
MAPQQQQTHP LQMPNPNVWS SHLGNMQQQQ QQGMGLRHDN LGQPQNMGNQ KPGYSSGGGS
DWTAMDPAIL SFRQFSFPQQ QQQNQMGPPQ MPPPPQQQQQ QPPPQDMFLQ HLSQQAAGFG
LGGGPPGGNG QMPNGQHHNS QGHLNVDASV QGMLEYLKTH QFV
//
