ID A0A1I8NDB7_MUSDO Unreviewed; 389 AA.
AC A0A1I8NDB7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Opsin Rh5 {ECO:0000313|RefSeq:XP_005175090.1};
GN Name=101900880 {ECO:0000313|EnsemblMetazoa:MDOA014013-PA};
GN Synonyms=LOC101900880 {ECO:0000313|RefSeq:XP_005175090.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA014013-PA};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA014013-PA}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA014013-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005175090.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005175090.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Visual pigments are the light-absorbing molecules that
CC mediate vision. They consist of an apoprotein, opsin, covalently linked
CC to cis-retinal. {ECO:0000256|ARBA:ARBA00002881}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663, ECO:0000256|RuleBase:RU000688}.
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DR RefSeq; XP_005175090.1; XM_005175033.3.
DR STRING; 7370.A0A1I8NDB7; -.
DR EnsemblMetazoa; MDOA014013-RA; MDOA014013-PA; MDOA014013.
DR GeneID; 101900880; -.
DR KEGG; mde:101900880; -.
DR VEuPathDB; VectorBase:MDOA014013; -.
DR eggNOG; KOG3656; Eukaryota.
DR OrthoDB; 3432893at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008020; F:G protein-coupled photoreceptor activity; IEA:UniProt.
DR GO; GO:0007602; P:phototransduction; IEA:UniProtKB-KW.
DR GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
DR CDD; cd15079; 7tmA_photoreceptors_insect; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001760; Opsin.
DR InterPro; IPR027430; Retinal_BS.
DR PANTHER; PTHR24240; OPSIN; 1.
DR PANTHER; PTHR24240:SF58; OPSIN RH5; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00577; OPSINRH3RH4.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR PROSITE; PS00238; OPSIN; 1.
PE 3: Inferred from homology;
KW Chromophore {ECO:0000256|ARBA:ARBA00022991};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Photoreceptor protein {ECO:0000256|ARBA:ARBA00022543};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Retinal protein {ECO:0000256|ARBA:ARBA00022925};
KW Sensory transduction {ECO:0000256|ARBA:ARBA00022606};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Vision {ECO:0000256|ARBA:ARBA00023305}.
FT TRANSMEM 57..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..338
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 389 AA; 44201 MW; 7CF5CDCEFE3AC5F4 CRC64;
MDSLERSEII GPVPFANYQN GSSLSSQNSP PNLGWHFPME YQHLIHEHWR SFPAPQIYYQ
AFLFMAFVAM LLCSLFGNGL VLWIFSTSKN LRTPSNLLII NLAIFDLTMA LNMPHYMINA
VLGYFWGGDL GCDIYAVIGG ISGQGAAVTN AFIAYDRYRT ISNPIDGRLN FPQIIIIIIM
TWLWTTPFSV LPLFHIWGHY IPEGFLTSCS FDYLSQDDET RYFVQSMFVW AYCIPMIIIC
VYYTKLFLHV RDHEKMLADQ AKKMNIKSLS ANQNAMSVEI RIAKAAMTIY MMYVFSWTPY
ATVSLLGTLN YRYMITPFAS MIPCCCAKLV SCLDPWVYAA SHPKYRAELE RRLPWLGVRE
RNAVPSVNSG SNVGDGCDSE TGTISMTNC
//
