ID A0A1I8NIJ3_MUSDO Unreviewed; 661 AA.
AC A0A1I8NIJ3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Nuclear protein localization protein 4 homolog isoform X1 {ECO:0000313|RefSeq:XP_005180041.1};
GN Name=101887729 {ECO:0000313|EnsemblMetazoa:MDOA015524-PB};
GN Synonyms=LOC101887729 {ECO:0000313|RefSeq:XP_005180041.1};
OS Musca domestica (House fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Musca.
OX NCBI_TaxID=7370 {ECO:0000313|EnsemblMetazoa:MDOA015524-PB};
RN [1] {ECO:0000313|EnsemblMetazoa:MDOA015524-PB}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|EnsemblMetazoa:MDOA015524-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_005180041.1}
RP IDENTIFICATION.
RC STRAIN=Aabys {ECO:0000313|RefSeq:XP_005180041.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NPL4 family.
CC {ECO:0000256|ARBA:ARBA00011025}.
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DR RefSeq; XP_005180041.1; XM_005179984.3.
DR STRING; 7370.A0A1I8NIJ3; -.
DR EnsemblMetazoa; MDOA015524-RB; MDOA015524-PB; MDOA015524.
DR GeneID; 101887729; -.
DR KEGG; mde:101887729; -.
DR VEuPathDB; VectorBase:MDOA015524; -.
DR eggNOG; KOG2834; Eukaryota.
DR OrthoDB; 5400828at2759; -.
DR Proteomes; UP000095301; Unassembled WGS sequence.
DR Proteomes; UP000694905; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR CDD; cd08061; MPN_NPL4; 1.
DR Gene3D; 3.40.140.10; Cytidine Deaminase, domain 2; 1.
DR Gene3D; 2.30.30.380; Zn-finger domain of Sec23/24; 1.
DR InterPro; IPR037518; MPN.
DR InterPro; IPR016563; Npl4.
DR InterPro; IPR007717; NPL4_C.
DR InterPro; IPR024682; Npl4_Ub-like_dom.
DR InterPro; IPR007716; NPL4_Zn-bd_put.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR12710; NUCLEAR PROTEIN LOCALIZATION 4; 1.
DR PANTHER; PTHR12710:SF0; NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG; 1.
DR Pfam; PF05021; NPL4; 1.
DR Pfam; PF11543; UN_NPL4; 1.
DR Pfam; PF05020; zf-NPL4; 1.
DR PIRSF; PIRSF010052; Polyub_prc_Npl4; 1.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR PROSITE; PS50249; MPN; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000694905};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 263..400
FT /note="MPN"
FT /evidence="ECO:0000259|PROSITE:PS50249"
FT DOMAIN 633..661
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 598..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 74764 MW; 652D2DD407EF46AC CRC64;
MAAMELEALF YRKRNIVYAF VRHRFFLMCK QSLVRVQSPE GIKRIEISPK ANLKDLFESV
QKALKVDGFG LFKERNLTKE IYSHTSQEVG SVLKHGDMIY LKQMAGTSSR RTSTTAIDNF
TSAKAITNSA TTTNSSDFKP SAAVKEDEVD ILLAKEDGLI KRERDSKLCR HAANGCCVHC
SPLEPYNENY LKEQKIKHLS FNSYIRKQTS GIDRGKYMVF EDINCRIKPG CREHPPWPRG
ICSKCQPSAI TLNRQIYRHV DNVMFENTTI VERFLNYWRT TGHQRMGFLY GTYEVNTDVP
LGIRAKVAAI YEPPQESSRD SIRLLNDENA EDVEEVAKAL GLKKVGWIFT DLITDDPAAG
TVKHIRGIET HFLTAQECIM AGELQNRHPN PCKYASNGVF GSKFVTVCVT GDNTKQVHME
GYAVSAQCMA LVRDNCLLPT KDAPELGYVR ESTDKQYVPD VYYKEKDQYG NEVQRLARPL
PVEYLLVDVP ASTPLQPQFT FSKYDKRQPF PVENRYLDGH LQDFNALSAY LSQWDDEDFL
EAISDFHLLV YLYKMDMLPM RQHMMPLLEA VRNKNPNMAY AFKKEEVWKL LESLIQASSS
GSGGTTSYPS ASSTNRTGAG GGSSSNAMES SGIDGNTWTC NHCTFINRSE LSSCEICSLP
R
//
