ID A0A1I8NM67_STOCA Unreviewed; 691 AA.
AC A0A1I8NM67;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=EXS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106092473 {ECO:0000313|EnsemblMetazoa:SCAU000232-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU000232-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU000232-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU000232-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013114801.1; XM_013259347.1.
DR AlphaFoldDB; A0A1I8NM67; -.
DR STRING; 35570.A0A1I8NM67; -.
DR EnsemblMetazoa; SCAU000232-RA; SCAU000232-PA; SCAU000232.
DR KEGG; scac:106092473; -.
DR VEuPathDB; VectorBase:SCAU000232; -.
DR OrthoDB; 3605858at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14477; SPX_XPR1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 3.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 464..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..567
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..175
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 427..630
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 647..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 691 AA; 81499 MW; 16AC64237306C2A0 CRC64;
MKFSKKLEAH LTPEWRQQYV SYKDLKQMIL NVSENGPIPQ IDSRRAINVF NQVFEEEFFS
ECRKQLKKVN TFYAEKLAEA TRRSNALSTS LSAIAEEFCL KKSSHSRYSC INAKDKLSTR
SKKATLEELR NAYSELYLSL VLLQNYKFLN HTGFRKILKK HDKLLHNDLG SRWFSENVDM
AYFFKNPEVE RLIEETEYNV TQYLENGDRA QAMKRLRVPP LEEVQQVGTV FRMGLLVGAF
MALFIQVVLT DLFTPATIKD KFYGVLLFRG PFYVILYLFF LGINVLHWRQ YGVNHVLIFE
INPRKRLTYS HILELHGGFG VLWCLCVLGF IYGPQLNISR YWFPLILLMA MMIFLLWPFN
AFHLSGRLWL LKLMGRVFAA PFFPVGFADF WFGDQLCSLA SCLLDLKYMM CFYTCNPKWS
DNFEASKCLE TDYLVNAIVL CLPAWFRFAQ SLRRYRDTKQ VHPFLVNAGK YFTTFPMVLF
ATLMAYHKAD YSSFFQNPYV WCYIFATCIQ SLYCYSWDIL RDFGLFEKFQ GKNIFLRDQI
VYPAKFYYFV IVVNLFLRFF WLFAMMVTAN CGVNNYLVDT AAGCLEIFRR YLWNYIRLEN
EHLNNVGQFR AVRDLFIAPI EDAKDRADLE KMMDEDDGVT NRRYTYLKEN NNGIEPTEND
KGPAHLEMMM DEDDGEENYN NTHFEDDDKE D
//
