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Database: UniProt
Entry: A0A1I8NM89_STOCA
LinkDB: A0A1I8NM89_STOCA
Original site: A0A1I8NM89_STOCA 
ID   A0A1I8NM89_STOCA        Unreviewed;       487 AA.
AC   A0A1I8NM89;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   08-MAY-2019, entry version 13.
DE   RecName: Full=Ubiquitinyl hydrolase 1 {ECO:0000256|SAAS:SAAS01044305};
DE            EC=3.4.19.12 {ECO:0000256|SAAS:SAAS01044305};
GN   Name=106092509 {ECO:0000313|VectorBase:SCAU000248-PA};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU000248-PA};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU000248-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU000248-PA};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU000248-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU000248-PA};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Thiol-dependent hydrolysis of ester, thioester, amide,
CC         peptide and isopeptide bonds formed by the C-terminal Gly of
CC         ubiquitin (a 76-residue protein attached to proteins as an
CC         intracellular targeting signal).; EC=3.4.19.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01117307};
CC   -!- SIMILARITY: Belongs to the peptidase C19 family.
CC       {ECO:0000256|SAAS:SAAS01045498}.
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DR   RefSeq; XP_013114845.1; XM_013259391.1.
DR   GeneID; 106092509; -.
DR   VectorBase; SCAU000248-RA; SCAU000248-PA; SCAU000248.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0004843; F:thiol-dependent ubiquitin-specific protease activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016578; P:histone deubiquitination; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR001607; Znf_UBP.
DR   Pfam; PF00443; UCH; 1.
DR   Pfam; PF02148; zf-UBP; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS00972; USP_1; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
DR   PROSITE; PS50271; ZF_UBP; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01044238};
KW   Metal-binding {ECO:0000256|SAAS:SAAS01044152};
KW   Protease {ECO:0000256|SAAS:SAAS01044292};
KW   Thiol protease {ECO:0000256|SAAS:SAAS01044269};
KW   Ubl conjugation pathway {ECO:0000256|SAAS:SAAS01044331};
KW   Zinc {ECO:0000256|SAAS:SAAS01044373};
KW   Zinc-finger {ECO:0000256|SAAS:SAAS01044352}.
FT   DOMAIN       44    103       UBP-type. {ECO:0000259|PROSITE:PS50271}.
FT   DOMAIN      158    482       USP. {ECO:0000259|PROSITE:PS50235}.
FT   ZN_FING      44    103       UBP-type. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00502}.
SQ   SEQUENCE   487 AA;  55295 MW;  6B696351699AD328 CRC64;
     MSESGCKHFQ SYVKEHSLDT YRILDAYFAA CINKDAREKK ALTCCCFECG SYGIQLFACL
     HCIYFGCRGS HIISHLRAKK HSISLELSHG TLYCNSCRDF IYDIRSREIA AVNRKLEAKD
     LQKSLTWTPW IPTPKETNLM LANPRRRNVK ANETLGLRGL INLGSTCFMN CIVQALIHTP
     LLSDYFLSDR HECSAKSSMK CLVCEVARLF QEFYSGSRTP LSLHRLLHLI WNHAKHLAGY
     EQQDAHEFFI ATLDVLHRHC IKAKAETESA NKSSSSTATH SNCPTQCNCI IDQIFTGMLQ
     SDVVCQSCKG VSTTIDPFWD ISLDLGEAHG GATPKSLIDC LERYTRAEHL GSSAKIKCST
     CKSYQESTKQ FSLRTLPSVA SFHLKRFEHS SLIDKKISTF ISFPVEFDMT PFMSEKNNAY
     GDFRYSLYAV VNHVGTIDAG HYTAYVRHHK DTWVKCDDHI ITTATLKQVL DSEGYLLFYH
     KNILEYE
//
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